Thrombosis inowanzova nemamiriro matatu anotevera:

1. Mwoyo nemudziyo weropa intima kukuvara

Iyo intima yeyakajairika moyo netsinga yeropa yakasimba uye yakatsetseka, uye masero endothelial akasimba anogona kuvharidzira kunamatira kweplatelet uye anticoagulation.Kana iyo yemukati membrane yakakuvadzwa, iyo coagulation system inogona kuvhurwa nenzira dzakawanda.

Yekutanga yakakuvadzwa intima inoburitsa tishu coagulation factor (coagulation factor III), iyo inomisa iyo extrinsic coagulation system.
Chechipiri, mushure mekunge intima yakuvadzwa, masero ekupedzisira anopera, necrosis, uye kudurura, achifumura ma collagen fibers pasi pe endothelium, nekudaro activate coagulation factor XII ye endogenous coagulation system uye kutanga endogenous coagulation system.Mukuwedzera, iyo intima yakakuvadzwa inova yakaoma, iyo inobatsira kune platelet deposition uye adhesion.Mushure mekuputika kweplatelet yakanamatira, zvakasiyana-siyana zveplatelet zvinhu zvinosunungurwa, uye iyo yose coagulation process inoshandiswa, zvichiita kuti ropa ribatane uye rigadzire thrombus.
Zvakasiyana-siyana zvemuviri, makemikari uye zvipenyu zvinhu zvinogona kukonzera kukuvadzwa kwemoyo intima, senge endocarditis munguruve erysipelas, pulmonary vasculitis mu bovine pneumonia, equine parasitic arteritis, majekiseni anodzokororwa muchikamu chimwe chete chetsinga, Kukuvara uye kuputsika kwemadziro etsinga yeropa. panguva yekuvhiyiwa.

2. Kuchinja kwehutano hwekuyerera kweropa

Zvikuru zvinoreva kunonoka kubuda kweropa, kuumbwa kwevortex uye kupera kwekuyerera kweropa.
Mumamiriro ezvinhu akajairika, kuyerera kweropa kunokurumidza, uye masero matsvuku eropa, maplatelet nezvimwe zvikamu zvinoiswa pakati pemudziyo weropa, unonzi axial flow;apo kuyerera kweropa kunoderera, masero matsvuku eropa uye maplatelet anoyerera pedyo nemadziro etsinga yeropa, inonzi side flow, iyo inowedzera thrombosis.ngozi inomuka.
Kuyerera kweropa kunoderera, uye endothelial masero ane hypoxic zvakanyanya, zvichikonzera kuderera uye necrosis yemasero ekupedzisira, kurasikirwa kwebasa ravo rekugadzira uye kuburitsa anticoagulant zvinhu, uye kuratidzwa kwe collagen, iyo inomutsa iyo coagulation system uye inosimudzira. thrombosis.
Kuyerera kweropa kunononoka kunogonawo kuita kuti iyo yakaumbwa thrombus ive nyore kugadzirisa pamadziro emidziyo yeropa uye kuramba ichiwedzera.

Nokudaro, thrombus inowanzoitika mumatsinga ane ropa rinononoka uye rinowanzoita eddy currents (pamavharuvhu).Aortic blood flow inokurumidza, uye thrombus haiwanzoonekwa.Maererano nenhamba, kuitika kwevenous thrombosis kanopfuura ka4 pane iyo arterial thrombosis, uye venous thrombosis inowanzoitika mukukundikana kwemoyo, mushure mekuvhiyiwa kana mumhuka dzinorwara dzakarara mudendere kwenguva yakareba.
Nokudaro, zvakakosha zvikuru kubatsira mhuka dzinorwara dzave dzakarara kwenguva refu uye mushure mekuvhiyiwa kuita mamwe mabasa akakodzera kudzivirira thrombosis.
3. Kuchinja kwezvinhu zveropa.

Kunyanya kunoreva kuwedzera kweropa coagulation.Zvakadai sokupisa kwakanyanya, kupera simba kwemvura, nezvimwewo kuisa pfungwa muropa, kukuvadzwa kwakanyanya, postpartum, uye kurasikirwa kwakanyanya kweropa mushure mekuvhiyiwa kukuru kunogona kuwedzera huwandu hwemaplatelet muropa, kuwedzera viscosity yeropa, uye kuwedzera zvirimo zvefibrinogen, thrombin nezvimwe zvinhu coagulation. mu plasma Kuwedzera.Zvinhu izvi zvinogona kukonzera thrombosis.