Activated Partial Thromboplastin Time Kit (APTT)

APTT kuyerwa ndiyo inonyanya kushandiswa kukiriniki yekuongorora bvunzo kuratidza iyo coagulation chiitiko che endogenous coagulation system.Inoshandiswa kuona endogenous coagulation factor defects uye zvine hukama inhibitors uye kuongorora chiitiko che activated protein C kuramba.Iine huwandu hwakawanda hwemashandisirwo maererano nekuongorora, kutarisa kweheparin therapy, kuongororwa kwekutanga kwekuparadzira intravascular coagulation (DIC), uye preoperative kuongorora.

Clinical kukosha:

APTT is a coagulation function test index inoratidza iyo endogenous coagulation nzira, kunyanya iyo yakazara chiitiko che coagulation zvinhu padanho rekutanga.Inoshandiswa zvakanyanya kuongorora uye kuona kukanganisa kweiyo coagulation zvinhu munzira inopera, senge factor Ⅺ, Ⅷ, Ⅸ, inogona zvakare kushandiswa kwekutanga kuongororwa kwezvirwere zvekubuda ropa uye murabhoritari yekutarisa heparin anticoagulation therapy.

1. Yakareba: inogona kuonekwa muhemophilia A, hemophilia B, chirwere chechiropa, intestinal sterilization syndrome, oral anticoagulants, diffuse intravascular coagulation, mild hemophilia;FXI, FXII kushomeka;ropa Anticoagulant zvinhu (coagulation factor inhibitors, lupus anticoagulants, warfarin kana heparin) yakawedzera;zvitsama zvikuru zveropa rakachengetwa zvakaisirwa.

2. Kupfupisa: Inogona kuonekwa mu hypercoagulable state, thromboembolic zvirwere, nezvimwewo.

Reference range of normal value

Iyo yakajairika referensi kukosha kweiyo activated partial thromboplastin nguva (APTT): 27-45 masekondi.

Zvekungwaririra

1. Dzivisa muenzaniso wehemolysis.Iyo hemolyzed specimen ine phospholipids yakaburitswa nekuputika kweyakakura tsvuku yeropa membrane, izvo zvinoita kuti APTT ive yakaderera pane yakayerwa kukosha kweiyo isiri-hemolyzed specimen.

2. Varwere havafaniri kuita mabasa akaoma mukati memaminitsi makumi matatu vasati vagamuchira ropa.

3. Mushure mekuunganidza ropa, zunza zvinyoronyoro chubhu yekuongorora ine sampu yeropa 3 kusvika ku5 nguva kuitira kuti unyatsobatanidza ropa reropa ne anticoagulant mu test tube.

4. Zviyero zveropa zvinofanira kutumirwa kunoongororwa nokukurumidza.