O le FIB o le fa'apuupuuga faaPeretania mo le fibrinogen, ma o le fibrinogen o se mea e fa'apipi'i ai.Ole maualuga ole toto ole tau ole FIB ole fa'auiga ole toto o lo'o i se tulaga hypercoagulable, ma e faigofie lava ona fausia le thrombus.

A maeʻa ona faʻagaoioia le faʻaogaina o le tagata, o le fibrinogen e avea ma fibrin monomer i lalo o le gaioiga a le thrombin, ma o le fibrin monomer e mafai ona faʻapipiʻi i le fibrin polymer, lea e fesoasoani mo le faʻavaeina o le toto ma e iai sona sao taua i le faagasologa o le coagulation.

O le fibrinogen e masani ona faʻapipiʻiina e le hepatocytes ma o se porotini e iai le galuega faʻapipiʻi.O lona tau masani o le va o le 2~4qL.O le fibrinogen o se mea e fesoʻotaʻi ma le coagulation, ma o lona faʻateleina e masani lava o se tali le faʻapitoa a le tino ma o se tulaga lamatia mo faʻamaʻi e fesoʻotaʻi ma le thromboembolism.
Coagulation FIB tau e mafai ona faʻateleina i le tele o faʻamaʻi, faʻamaʻi masani poʻo mea faʻamaʻi, gaʻo toto maualuga, toto maualuga

Ma'i maualuga, ma'i fatu fatu, ma'i suka, mamapala, ma'i feso'ota'i, ma'i fatu, ma tuma ma'i.pe a mafatia i faʻamaʻi uma o loʻo taʻua i luga e mafai ona mafua ai le faʻalavelave toto.O le mea lea, ole maualuga ole toto maualuga ole tau FIB e faasino ile tulaga ole toto maualuga.