D-dimer e masani ona faʻaaogaina o se tasi o faʻailoga taua masalomia o le PTE ma le DVT i le falemaʻi.Na faapefea ona oo mai?

Plasma D-dimer o se oloa fa'aleagaina fa'apitoa na gaosia e le plasmin hydrolysis pe a uma ona fa'afeso'ota'i le monomer fibrin e ala i le fa'agaoioia o mea XIII.O se fa'ailoga fa'apitoa ole fa'agasologa ole fibrinolysis.D-dimers e maua mai i koluse feso'ota'iga fibrin clots lysed e plasmin.Afai lava o loʻo i ai le thrombosis malosi ma le fibrinolytic gaioiga i totonu o le toto o le tino, o le D-dimer o le a faʻateleina.Myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, taotoga, tuma, faʻasalalauina o le intravascular coagulation, faʻamaʻi ma le necrosis o mea e mafai ona oʻo atu ai i le D-dimer maualuga.Aemaise lava mo tagata matutua ma falemaʻi, ona o le bacteremia ma isi faʻamaʻi, e faigofie ona faʻaleagaina le toto toto ma taʻitaʻia ai le D-dimer.

O le D-dimer e fa'aalia ai le galuega fibrinolytic.Faʻateleina pe lelei vaʻaia i le hyperfibrinolysis lona lua, e pei o le hypercoagulable state, faʻasalalauina intravascular coagulation, faʻamaʻi fatu, faʻateʻaina o totoga, togafitiga thrombolytic, ma isi. o le fibrinolytic system (e pei o le DIC, thrombus eseese) ma faʻamaʻi e fesoʻotaʻi ma le fibrinolytic system (e pei o le tuma, maʻi maʻitaga), ma le mataʻituina o togafitiga o le thrombolytic.

O maualuga maualuga o le D-dimer, o se oloa faʻaleagaina fibrin, e faʻaalia ai le faʻaleagaina soo o fibrin i vivo.O le mea lea, fibrous D-dimer o se faailoga autu o le loloto vein thrombosis (DVT), pulmonary embolism (PE), faʻasalalau intravascular coagulation (DIC).

O le tele o faʻamaʻi e mafua ai le faʻagaoioia o le coagulation system ma / poʻo le fibrinolytic system i totonu o le tino, e mafua ai le faʻatupulaia o le maualuga o le D-dimer, ma o lenei faʻagaioiga e fesoʻotaʻi vavalalata ma le tulaga, ogaoga ma togafitiga o le faʻamaʻi, o lea i nei faʻamaʻi. O le su'esu'eina o le maualuga ole D-dimer e mafai ona fa'aaogaina e fai ma fa'ailoga fa'ailoga mo fa'ama'i fa'ama'i, fa'ata'ita'iga ma ta'iala mo togafitiga.

Fa'aaogāina ole D-dimer ile vein thrombosis loloto

Talu mai Wilson et al.muamua faʻaaogaina oloa faʻaleagaina fibrin mo le suʻesuʻeina o le pulmonary embolism i le 1971, o le mauaina o le D-dimer ua faia se sao tele i le suʻesuʻeina o le pulmonary embolism.Faatasi ai ma nisi o auala e sili ona maaleale, o le D-dimer Body value o loʻo i ai se aʻafiaga leaga lelei mo le pulmonary embolism, ma o lona tau e 0.99.O se taunuuga le lelei e mafai ona taofiofia ai le pulmonary embolism, ma faʻaitiitia ai suʻesuʻega osofaʻi, e pei o le suʻeina o le ea ma le pulmonary angiography;aloese mai le tauaso anticoagulation therapy.D - O le faʻaogaina o le dimer e fesoʻotaʻi ma le nofoaga o le thrombus, faʻatasi ai ma le maualuga o faʻasalalauga i lala tetele o le ogalaau pulmonary ma lalo ifo o laʻau i lala laiti.

Ole plasma D-dimers leaga e fa'asalaina le avanoa ole DVT.Angiography faʻamaonia le DVT e 100% lelei mo D-dimer.E mafai ona faʻaaogaina mo togafitiga thrombolytic ma le heparin anticoagulation taʻiala ma le mataʻituina o le aoga.

D-dimer e mafai ona atagia ai suiga i le tele o le thrombus.Afai e toe faʻateleina le anotusi, e taʻu mai ai le toe tupu o le thrombus;i le taimi o togafitiga, e faʻaauau pea ona maualuga, ma e le suia le tele o le thrombus, e faʻaalia ai e le aoga le togafitiga.