Ole Taua ole Falema'i ole Coagulation


Tusitala: Sui   

1. Taimi Prothrombin (PT)

O lo'o atagia mai ai le tulaga o le fa'aogaina o le tino, lea e masani ona fa'aogaina ai le INR e mata'ituina ai vaila'au fa'ama'i.O le PT o se faʻailoga taua mo le suʻesuʻeina o le prethrombotic state, DIC ma le ate.E faʻaaogaina e fai ma suʻega suʻega mo le faʻaogaina o le faʻaogaina o le tino ma o se auala taua foʻi o le faʻamaʻi faʻamaʻi faʻamaʻi faʻamaʻi faʻamaʻi faʻamaʻi faʻamaʻi toto.

PTA<40% o loʻo faʻaalia ai le necrosis tele o sela o le ate ma faʻaitiitia le faʻaogaina o mea faʻapipiʻi.Mo se faʻataʻitaʻiga, 30%

O le faaumiumi o loo vaaia i:

a.O le tele ma le ogaoga o le fa'aleagaina o le ate e mafua ona o le fa'atupuina o le prothrombin ma mea fa'atupu fa'alavelave.

e.Le lava VitK, VitK e manaʻomia e faʻapipiʻi mea II, VII, IX, ma X. A le lava VitK, faʻaitiitia le gaosiga ma faʻaumiumi le taimi o le prothrombin.E vaaia foi i le jaundice obstructive.

C. DIC (diffuse intravascular coagulation), lea e faʻaaogaina ai le tele o mea e faʻafefe ai ona o le tele o le microvascular thrombosis.

o.Fa'ato'ato'a toto toto, prothrombin fanau mai le leai o togafitiga fa'ama'i.

Faapuupuu vaaia i:

Pe a iai le toto i se tulaga hypercoagulable (pei o le DIC vave, myocardial infarction), faʻamaʻi thrombotic (e pei o le cerebral thrombosis), ma isi.

 

2. Taimi thrombin (TT)

E atagia mai ai le taimi e liu fibrinogen i fibrin.

O le faʻaumiumi o loʻo vaʻaia i: faʻateleina le heparin poʻo mea heparinoid, faʻateleina gaioiga AT-III, aofaʻi faʻaletonu ma le lelei o fibrinogen.DIC hyperfibrinolysis stage, maualalo (leai) fibrinogenemia, hemoglobinemia faaletonu, toto fibrin (proto) degradation products (FDPs) faateleina.

O le fa'aitiitiga e leai se taua fa'afoma'i.

 

3. Fa'agaoioia vaega ole thromboplastin taimi (APTT)

E masani ona atagia ai le tulaga o le faiga o le coagulation endogenous ma e masani ona faʻaaogaina e mataʻituina ai le vailaʻau o le heparin.Fa'ata'ita'iina le maualuga o mea taua VIII, IX, XI, XII i totonu o le plasma, o se su'ega su'esu'e mo le fa'aogaina o le tino.APTT e masani ona faʻaaogaina e mataʻituina ai togafitiga faʻamaʻi heparin.

O le faaumiumi o loo vaaia i:

a.Leai o mea fa'a'au'au VIII, IX, XI, XII:

e.Coagulation factor II, V, X ma le faʻaitiitia o fibrinogen toalaiti;

C. O lo'o i ai vaila'au fa'amalosi e pei o le heparin;

d, fa'ateleina oloa fa'aleagaina fibrinogen;u, DIC.

Faapuupuu vaaia i:

Tulaga Hypercoagulable: Afai e ulu atu le vailaʻau procoagulant i totonu o le toto ma faʻateleina le gaioiga o mea faʻapipiʻi, ma isi.

 

4.Plasma fibrinogen (FIB)

O lo'o atagia mai ai mea o lo'o iai fibrinogen.Plasma fibrinogen o le porotini fa'ato'a fa'ato'a fa'atasi ai ma mea e sili ona maualuga o mea fa'atutu uma, ma o se mea e tali atu ai i le vaega.

Faʻateleina vaʻaia i: mu, maʻi suka, faʻamaʻi pipisi, mama mama, kanesa, endocarditis siama subacute, maitaga, niumonia, cholecystitis, pericarditis, sepsis, maʻi nephrotic, uremia, faʻamaʻi faʻamaʻi.

Fa'aiti'itia va'aia i: Fa'aletonu fibrinogen fanau mai, DIC fa'ama'imau vaega ole hypocoagulation, fibrinolysis muamua, hepatitis tuga, ate cirrhosis.

 

5.D-Dimer (D-Dimer)

E atagia mai ai le galuega o le fibrinolysis ma o se faʻailoga e iloa ai le i ai poʻo le leai o le thrombosis ma lona lua fibrinolysis i le tino.

O le D-dimer o se oloa faʻaleagaina faʻapitoa o fibrin fesoʻotaʻi, lea e faʻateleina i le plasma pe a maeʻa le thrombosis, o lea o se faailoga mole mole taua mo le suʻesuʻeina o le thrombosis.

O le D-dimer na fa'atuputeleina tele i le maualuga o le fibrinolysis hyperactivity, ae le'i fa'ateleina i le hyperactivity muamua o le fibrinolysis, o se fa'ailoga taua mo le fa'avasegaina o le lua.

O le faʻaopoopoga o loʻo vaʻaia i faʻamaʻi e pei o le vein thrombosis loloto, pulmonary embolism, ma le DIC secondary hyperfibrinolysis.