O se tino masani o loʻo i ai le faʻaogaina atoatoa ma le faʻaogaina o le faʻaogaina.O le faiga fa'ato'aga ma le faiga fa'ato'aga e fa'atumauina le paleni malosi e fa'amautinoa ai le fa'amama o le tino ma le sologa lelei o le tafe toto.O le taimi lava e faʻalavelave ai le paleni o galuega faʻamalosi ma le faʻamaʻi, o le a taʻitaʻia ai le toto ma le thrombosis.

1. Galuega fa'ato'a o le tino

O le faiga o le coagulation e masani lava ona aofia ai mea faʻapipiʻi.O mea o lo'o a'afia sa'o i le fa'aupuga e ta'ua o mea fa'ato'a.E 13 fa'ailoga fa'atosina fa'amaonia.

O lo'o iai auala fa'atosina fa'atosina ma ala fa'atosina mai fafo mo le fa'agaoioia o mea taua.

O lo'o talitonuina i le taimi nei o le fa'agaoioia o le fa'aogaina o le fa'aogaina o le fa'aogaina o le tino e fa'amataina e le vaega o le tino e tele sona sao i le amataga o le fa'atupuina.O le vavalalata vavalalata i le va o le faʻaogaina o totonu ma fafo o loʻo i ai se sao taua i le amataina ma le faʻamautuina o le faʻagasologa o le coagulation.

2. Galuega fa'aanticoagulant a le tino

O le fa'ama'i fa'ama'i e aofia ai le fa'aogaina o le tino ma le tino.

①Cell anticoagulation system

E faasino i le phagocytosis o le coagulation factor, tissue factor, prothrombin complex ma soluble fibrin monomer e le mononuclear-phagocyte system.

②Faiga fa'amalo ole sua ole tino

E aofia ai: serine protease inhibitors, protein C-based protease inhibitors ma tissue factor pathway inhibitors (TFPI).

3. Fibrinolytic faiga ma ana galuega tauave

E masani ona aofia ai plasminogen, plasmin, plasminogen activator ma fibrinolysis inhibitor.

Le matafaioi o le fibrinolytic system: faʻamavae fibrin clots ma faʻamautinoa le sologa lelei o le toto;auai i le toe faʻaleleia o aano o le tino ma le faʻafouina o vascular.

4. Le matafaioi a sela endothelial vascular i le faagasologa o le coagulation, anticoagulation ma fibrinolysis

① Fa'atupu mea eseese fa'aolaola;

② Faʻatonutonu le faʻamalo toto ma le faʻamaʻiina o galuega;

③Fetuutuunai le galuega o le fibrinolysis system;

④ Faʻatonutonu le faʻalavelave toto;

⑤ Auai i le soalaupulega o le mumū;

⑥Taumau le galuega ole microcirculation, ma isi.

Coagulation ma fa'aletonu fa'ama'i

1. Fa'aletonu i mea fa'ato'a.

2. Fa'aletonu o mea fa'aanticoagulant ile plasma.

3. Fa'aletonu ole vaega ole fibrinolytic ile plasma.

4. Fa'aletonu o sela toto.

5. Ala toto e le masani ai.