Nthawi ya Thrombin (TT) ndi nthawi ya prothrombin (PT) ndizozindikiro zozindikiritsa ntchito za coagulation, kusiyana pakati paziwirizi kumakhala pakuzindikira zinthu zosiyanasiyana za coagulation.

Nthawi ya Thrombin (TT) ndi chizindikiro cha nthawi yofunikira kuti mudziwe kutembenuka kwa plasma prothrombin kukhala thrombin.Amagwiritsidwa ntchito kwambiri powunika momwe fibrinogen imagwirira ntchito komanso coagulation factor I, II, V, VIII, X ndi XIII mu plasma.Panthawi yozindikira, minofu yambiri ya prothrombin ndi calcium ions imawonjezeredwa kuti atembenuzire prothrombin mu plasma kukhala thrombin, ndipo nthawi yotembenuka imayesedwa, yomwe ndi mtengo wa TT.

Prothrombin time (PT) ndi index yodziwira zochitika za magazi coagulation kunja kwa magazi coagulation system.Panthawi yozindikira, kuchuluka kwa coagulation factor (monga coagulation factor II, V, VII, X ndi fibrinogen) kumawonjezeredwa kuti ayambitse dongosolo la coagulation, ndipo nthawi yopangira magazi imayesedwa, yomwe ndi mtengo wa PT.Mtengo wa PT umawonetsa momwe ntchito ya coagulation factor ilili kunja kwa coagulation system.

Tiyenera kuzindikira kuti zizindikiro zonse za TT ndi PT ndizo zizindikiro zomwe zimagwiritsidwa ntchito kawirikawiri poyesa ntchito ya coagulation, koma ziwirizi sizingalowe m'malo mwa wina ndi mzake, ndipo zizindikiro zozindikiritsa zoyenera ziyenera kusankhidwa malinga ndi chikhalidwe chenichenicho.Panthawi imodzimodziyo, ziyenera kuzindikiridwa kuti kusiyana kwa njira zodziwira ndi ma reagents kungakhudze kulondola kwa zotsatira, ndipo tcheru chiyenera kuperekedwa ku ntchito zovomerezeka muzochita zachipatala.