PT imatanthawuza nthawi ya prothrombin muzamankhwala, ndipo APTT imatanthawuza kukhazikitsidwa kwa nthawi ya thromboplastin muzamankhwala.Ntchito ya magazi coagulation ya thupi la munthu ndi yofunika kwambiri.Ngati magazi coagulation ntchito ndi yachilendo, zingachititse kuti thrombosis kapena magazi, zomwe zingawononge kwambiri moyo wa wodwalayo.Kuwunika kwachipatala kwa PT ndi APTT kungagwiritsidwe ntchito ngati muyeso wogwiritsa ntchito mankhwala ena oletsa magazi m'machitidwe azachipatala.Ngati miyeso yoyezerayo ndi yokwera kwambiri, zikutanthauza kuti mlingo wa anticoagulant uyenera kuchepetsedwa, apo ayi magazi amatuluka mosavuta.

1. Nthawi ya Prothrombin (PT): Ndi imodzi mwa zizindikiro zowonongeka kwambiri za dongosolo la coagulation ya magazi a munthu.Ndizofunikira kwambiri kutalikitsa nthawi kwa masekondi opitilira 3 muzochita zamankhwala, zomwe zitha kuwonetsa ngati kukomoka kwa exogenous coagulation ndikwachilendo.Kutalikitsa nthawi zambiri kumawonedwa mu congenital coagulation Kuperewera kwa Factor, kwambiri cirrhosis, kulephera kwa chiwindi ndi matenda ena.Kuonjezera apo, mlingo wochuluka wa heparin ndi warfarin ungayambitsenso PT yaitali;

2. Activated partial thromboplastin time (APTT): Ndilolondo lomwe limawonetsa momwe magazi amagwirira ntchito pochita zachipatala.Kutalikitsa kwakukulu kwa APTT kumawonekera makamaka mu kuperewera kwa congenital kapena kupeza coagulation factor, monga hemophilia ndi systemic lupus erythematosus.Ngati mlingo wa mankhwala a anticoagulant omwe amagwiritsidwa ntchito chifukwa cha thrombosis ndi wachilendo, zipangitsanso kuti APTT italitsidwe.Ngati mtengo woyezedwa uli wochepa, ganizirani kuti wodwalayo ali mu hypercoagulable state, monga deep vein thrombosis.

Ngati mukufuna kudziwa ngati PT ndi APTT yanu ndizabwinobwino, muyenera kufotokozera momwe zimakhalira.Mtundu wabwinobwino wa PT ndi masekondi 11-14, ndipo mtundu wamba wa APTT ndi masekondi 27-45.Kutalikitsa kwa PT kwa masekondi opitilira 3 kumakhala ndi tanthauzo lalikulu lachipatala, ndipo kukwera kwa APTT kwa masekondi opitilira 10 kumakhala ndi tanthauzo lachipatala.