Coagulation INR imatchedwanso PT-INR kuchipatala, PT ndi nthawi ya prothrombin, ndipo INR ndi chiŵerengero chapadziko lonse lapansi.PT-INR ndi chinthu choyezera mu labotale ndi chimodzi mwazowonetsa zoyezetsa magazi a coagulation, omwe ali ndi tanthauzo lofunikira pazachipatala.

Mtundu wabwinobwino wa PT ndi 11s-15s kwa akulu, ndi 2s-3s kwa ana obadwa kumene.Mulingo wabwinobwino wa PT-INR kwa akulu ndi 0.8-1.3.Ngati mankhwala a anticoagulant, monga mapiritsi a warfarin sodium, agwiritsidwa ntchito, mitundu yosiyanasiyana ya PT-INR ikulimbikitsidwa kuti iziwongoleredwa pa 2.0-3.0 kuti ikwaniritse zotsatira zabwino za anticoagulant.Warfarin sodium mapiritsi amagwiritsidwa ntchito chipatala anticoagulants zochizira zakuya mtsempha thrombosis kapena thrombotic matenda chifukwa cha atria fibrillation, valvular matenda, m`mapapo mwanga embolism, etc. PT-INR ndi ndondomeko yofunika kuwunika coagulation ntchito mu thupi, ndipo ndi komanso maziko a madokotala kusintha mlingo wa warfarin sodium mapiritsi.Ngati PT-INR ndiyokwera kwambiri, izi zikuwonetsa chiwopsezo chochulukira magazi.Ngati mlingo wa PT-INR ndi wotsika kwambiri, ukhoza kusonyeza kuopsa kwa magazi.

Mukayesa PT-INR, nthawi zambiri pamafunika kumwa magazi a venous.Njira imeneyi ilibe lamulo lodziŵika bwino losala kudya, ndipo odwala safunika kusamala kaya adye kapena ayi.Magazi akakoka, tikulimbikitsidwa kugwiritsa ntchito thonje wosabala kuti asiye kutuluka magazi, kuti mupewe kuchuluka kwa PT-INR, kusakhazikika bwino kumayambitsa mabala a subcutaneous.