FIB ndi chidule cha Chingerezi cha fibrinogen, ndipo fibrinogen ndi coagulation factor.Kuchuluka kwa magazi kwa FIB kumatanthauza kuti magazi ali mu hypercoagulable state, ndipo thrombus imapangidwa mosavuta.

Pambuyo poyambitsa makina a coagulation, fibrinogen imakhala fibrin monomer pansi pa zochita za thrombin, ndipo fibrin monomer imatha kuphatikizira mu fibrin polima, yomwe imathandiza kupanga magazi kuundana ndipo imagwira ntchito yofunika kwambiri pakupanga magazi.

Fibrinogen imapangidwa makamaka ndi hepatocytes ndipo ndi mapuloteni okhala ndi coagulation.Mtengo wake wabwinobwino uli pakati pa 2 ~ 4qL.Fibrinogen ndi chinthu chokhudzana ndi coagulation, ndipo kuwonjezeka kwake nthawi zambiri sikumakhala kwenikweni kwa thupi ndipo ndi chiopsezo cha matenda okhudzana ndi thromboembolism.
Coagulation FIB mtengo ukhoza kuwonjezeka mu matenda ambiri, wamba chibadwa kapena zotupa, lipids mkulu magazi, kuthamanga kwa magazi.

Matenda a mtima, matenda a shuga, chifuwa chachikulu, matenda opatsirana, matenda a mtima, ndi zotupa zoopsa.pamene akuvutika ndi matenda onse omwe ali pamwambawa angayambitse kuphulika kwa magazi.Chifukwa chake, kuchuluka kwambiri kwa magazi kwa FIB kumatanthawuza mkhalidwe wamagazi okwera kwambiri.