D-dimer imachokera ku mtanda wolumikizana ndi fibrin clot wosungunuka ndi plasmin.Imawonetsa makamaka ntchito ya lytic ya fibrin.Iwo makamaka ntchito matenda a venous thromboembolism, kwambiri mtsempha thrombosis ndi m`mapapo mwanga embolism kuchipatala kuchita.D-dimer qualitative test ndi yolakwika, ngati kuyesa kochulukira kuyenera kukhala kosakwana 200μg/L.

Kuwonjezeka kwa D-dimer kapena zotsatira zabwino zoyezetsa nthawi zambiri zimawonedwa m'matenda okhudzana ndi hyperfibrinolysis yachiwiri, monga hypercoagulable state, kufalitsa intravascular coagulation, matenda aimpso, kukanidwa kwa kuyika ziwalo, ndi chithandizo cha thrombolytic.Komanso, pamene thrombosis adamulowetsa m'mitsempha ya magazi, kapena matenda limodzi ndi fibrinolytic ntchito, D-dimer adzakhala kwambiri kuchuluka.matenda wamba monga myocardial infarction, m`mapapo mwanga embolism, m`munsi malekezero deep mtsempha thrombosis, ubongo infarction etc.;matenda ena, opaleshoni, matenda a chotupa, ndi minofu necrosis kumayambitsanso D-dimer;Kuphatikiza apo, matenda ena amtundu wa autoimmune, monga rheumatic endocarditis, nyamakazi, systemic Lupus erythematosus, ndi zina zambiri, angayambitsenso D-dimer.

Kuphatikiza pakuzindikira matenda, kudziwa kuchuluka kwa D-dimer kumatha kuwonetsanso kuchuluka kwa thrombolytic zotsatira zamankhwala pazachipatala.Mbali za matenda, ndi zina zotero, ndizothandiza.

Pankhani ya D-dimer yokwezeka, thupi limakhala pachiwopsezo chachikulu cha thrombosis.Panthawiyi, matenda oyambirira ayenera kuzindikiridwa mwamsanga, ndipo pulogalamu yopewera thrombosis iyenera kuyambitsidwa malinga ndi chiwerengero cha DVT.Mankhwala ena akhoza kusankhidwa anticoagulation mankhwala, monga subcutaneous jekeseni wa otsika maselo kulemera heparin kashiamu kapena rivaroxaban, amene ali ndi njira zodzitetezera pa mapangidwe thrombosis.Amene ali ndi zotupa thrombotic ayenera thrombolytic chotupa mwamsanga mu nthawi golide, ndipo Nthawi ndi nthawi kuwunika D-dimer.