Anthu ena omwe amanyamula chachisanu cha Leiden sangadziwe.Ngati pali zizindikiro, choyamba nthawi zambiri chimakhala kutsekeka kwa magazi m'chigawo china cha thupi..Malingana ndi malo a magazi, amatha kukhala ochepa kwambiri kapena owopsa.
Zizindikiro za thrombosis ndi:
•Kupweteka
•Kufiira
•Kutupa
•Malungo
• Deepveinclot thrombosis (deepveinclot, DVT) nthawi zambiri m'munsi ndi zizindikiro zofanana koma kutupa kwambiri.
Magazi amalowa m'mapapo ndikuyambitsa pulmonary embolism, yomwe ingawononge mapapu ndipo ikhoza kupha moyo.Zizindikiro zake ndi izi:
•Kupweteka pachifuwa kapena kusapeza bwino, nthawi zambiri kumakulitsidwa ndi kupuma kwambiri kapena kutsokomola
•Hemoptysis
•Kumavuta kupuma
•Kuwonjezeka kwa mtima kapena arrhythmia
•Kutsika kwambiri kwa magazi, chizungulire kapena kukomoka
•Kupweteka, kufiira ndi kutupa
•Mitsempha yakuya ya thrombosis ya m'munsi Kupweteka kwa chifuwa ndi kusamva bwino
•Kumavuta kupuma
•Pulmonary embolism
Leiden Fifth Factor imawonjezeranso chiopsezo cha mavuto ndi matenda ena
• Deep vein thrombosis: kumatanthauza kukhuthala kwa magazi ndi kupangika kwa zitseko za magazi m'mitsempha, zomwe zimawonekera mbali iliyonse ya thupi, koma nthawi zambiri mwendo umodzi wokha.Makamaka pankhani ya kuthawa mtunda wautali ndi zina mtunda wautali kukhala maola angapo.
•Mavuto apakati: Amayi omwe ali ndi gawo lachisanu la Leiden ali ndi mwayi wopita padera kuwirikiza kawiri kapena katatu mu trimester yachiwiri kapena yachitatu ya mimba.Zitha kuchitika kangapo, komanso zimawonjezera chiopsezo cha kuthamanga kwa magazi panthawi yomwe ali ndi pakati (madokotala angatchule kuti pre-eclampsia kapena kulekanitsidwa msanga kwa placenta ndi khoma la chiberekero (lomwe limadziwikanso kuti placenta abruption). chifukwa Mwana amakula pang'onopang'ono.
•Pulmonary embolism: The thrombus imachoka pamalo ake oyambirira ndipo imalola magazi kupita m'mapapo, zomwe zingalepheretse mtima kupopa ndi kupuma.