APTT ndi chidule cha Chingerezi cha nthawi ya prothrombin yomwe idakhazikitsidwa pang'ono.APTT ndi mayeso owunikira omwe akuwonetsa njira yokhazikika ya coagulation.APTT yotalikirapo ikuwonetsa kuti chinthu china chophatikizira magazi chomwe chimakhudzidwa ndi njira ya coagulation yamunthu sichikuyenda bwino.Pambuyo pa APTT yayitali, wodwalayo amakhala ndi zizindikiro zoonekeratu za magazi.Mwachitsanzo, odwala haemophilia A, haemophilia B, ndi von Willebrand matenda onse adzakhala yaitali APTT, ndipo wodwala ecchymosis pakhungu ndi mucous nembanemba, ndi minofu magazi., magazi olowa, hematoma, etc. Makamaka kwa odwala omwe ali ndi hemophilia A, kupunduka kwa olowa ndi minofu atrophy nthawi zambiri amasiyidwa pambuyo pa kutengeka kwa hematoma chifukwa cha synovitis chifukwa cha magazi olowa m'magazi, omwe amakhudza kwambiri thanzi.Kuphatikiza apo, kufalikira kwa intravascular coagulation, matenda oopsa a chiwindi ndi matenda ena kumayambitsanso kukulitsa kwa APTT, zomwe zingayambitse kuvulaza thupi la munthu.
Mtengo waukulu wa Apt umasonyeza kuti wodwalayo akhoza kudwala matenda a magazi.Matenda obwera chifukwa chotuluka magazi ndi monga congenital coagulation factor deficiency ndi hemophilia.Kachiwiri, akuganiziridwa kuti amayamba chifukwa cha matenda a chiwindi kapena obstructive jaundice kapena thrombotic matenda.Komanso sizikulamulidwa kuti zimayambitsidwa ndi mphamvu ya mankhwala osokoneza bongo, monga kugwiritsa ntchito nthawi yaitali mankhwala oletsa magazi.Zachipatala, kuyezetsa aptt angagwiritsidwe ntchito kuweruza ngati coagulation ntchito mu thupi la wodwalayo ndi bwino.Ngati ndi chifukwa cha chodabwitsa chifukwa hemophilia, Ndi bwino kutsatira malangizo a dokotala kusiya magazi kapena kugwiritsa ntchito prothrombin zovuta mankhwala.