Thrombosis ndi njira imene magazi oyenda coagulates ndi kusanduka magazi kuundana, monga ubongo mtsempha wamagazi thrombosis (kuchititsa ubongo infarction), kwambiri mtsempha thrombosis m`munsi malekezero, etc. The anapanga magazi kuundana ndi thrombus;magazi opangidwa m'mbali ina ya mtsempha wamagazi amasuntha motsatira magazi ndikutsekeredwa ku mtsempha wina wamagazi.Njira ya embolization imatchedwa embolism.The deep vein thrombosis ya miyendo ya m'munsi imagwa, imasuntha, ndipo imatsekeredwa ku pulmonary artery ndipo imayambitsa pulmonary embolism.;Kutsekeka kwa magazi komwe kumayambitsa embolism kumatchedwa embolus panthawiyi.
M'moyo watsiku ndi tsiku, kutsekeka kwa magazi kumatulutsidwa pambuyo poyimitsa mphuno;kumene kuvulala kwavulala, chotupa nthawi zina chimamveka, chomwe chimakhalanso ndi thrombus;ndipo myocardial infarction imayamba chifukwa cha kusokonezeka kwa magazi pamene mtsempha wamagazi womwe umakhala wosakhazikika pamtima watsekeka ndi kutsekeka kwa magazi Ischemic necrosis ya myocardium.
Pansi pa zochitika zakuthupi, ntchito ya thrombosis ndikuyimitsa magazi.Kukonzanso kwa minofu ndi ziwalo zonse kuyenera kuyamba kuyimitsa magazi.Hemophilia ndi coagulopathy yomwe imayamba chifukwa cha kusowa kwa zinthu zomwe zimalumikizana.Ndizovuta kupanga thrombus mu gawo lovulala ndipo silingathe kuletsa kutuluka kwa magazi ndikuyambitsa magazi.Mitundu yambiri ya hemostatic thrombosis imakhala kunja kwa mtsempha wamagazi kapena kumene chotengera chamagazi chasweka.
Ngati magazi atuluka mumtsempha wamagazi, kutuluka kwa magazi mumtsempha wamagazi kumatsekedwa, kutuluka kwa magazi kumachepa, kapena ngakhale kutuluka kwa magazi kumasokonekera.Ngati thrombosis imapezeka m'mitsempha, imayambitsa chiwalo / minyewa ya ischemia komanso ngakhale necrosis, monga infarction ya myocardial, cerebral infarction, ndi m'munsi mwa necrosis / kudula.Thrombus yomwe imapangidwa m'mitsempha yakuya ya m'munsi mwa mitsempha ya m'munsi sikuti imakhudza kutuluka kwa magazi a venous mu mtima ndipo imayambitsa kutupa kwa mitsempha ya m'munsi, komanso imagwera pansi pa vena cava yotsika, atrium yoyenera ndi ventricle yolondola kuti ilowe ndikutsekera mkati. pulmonary embolism, yomwe imayambitsa pulmonary embolism.Matenda omwe amafa kwambiri.
Kuyamba kwa thrombosis
Nthawi zambiri, kugwirizana koyamba kwa thrombosis ndi kuvulala, zomwe zingakhale zoopsa, opaleshoni, kupasuka kwa zolengeza mu mitsempha, kapena kuwonongeka kwa endothelial chifukwa cha matenda, chitetezo cha mthupi ndi zina.Njira yopangira thrombus yomwe imayambitsidwa ndi kuvulala imatchedwa exogenous coagulation system.Nthawi zina, kuchepa kwa magazi kapena kuchepa kwa magazi kumatha kuyambitsanso thrombosis, yomwe ndi njira yolumikizirana, yotchedwa endogenous coagulation system.
Choyamba hemostasis
Pamene chovulalacho chimakhudza mitsempha ya magazi, mapulateleti amayamba amamatira kuti apange gawo limodzi kuti aphimbe bala, ndiyeno amalowetsedwa kuti agwirizane kuti apange clumps, omwe ndi platelet thrombi.Njira yonseyi imatchedwa primary hemostasis.
Secondary hemostasis
Chovulalacho chimatulutsa chinthu chophatikizika chotchedwa tissue factor, chomwe chimayambitsa endogenous coagulation system kupanga thrombin atalowa m'magazi.Thrombin kwenikweni ndi chothandizira chomwe chimasintha mapuloteni a coagulation m'magazi, ndiko kuti, fibrinogen kukhala fibrin., Njira yonseyi imatchedwa secondary hemostasis.
"Kuyanjana Kwabwino"Thrombosis
M'kati mwa thrombosis, gawo loyamba la hemostasis (kumatira kwa platelet, kutsegula ndi kuphatikizira) ndi gawo lachiwiri la hemostasis (kupanga thrombin ndi mapangidwe a fibrin) zimagwirizana.Gawo lachiwiri la hemostasis limatha kuchitika pafupipafupi pamaso pa mapulateleti, ndipo thrombin yomwe idapangidwayo imayambitsanso mapulateleti.Awiriwa amagwira ntchito limodzi ndikugwira ntchito limodzi kuti amalize njira ya thrombosis.