Thrombosis ndi njira yachibadwa ya thupi kuti magazi aziundana.Popanda thrombus, anthu ambiri amatha kufa chifukwa cha "kutaya magazi kwambiri".
Aliyense wa ife wavulazidwa ndikutuluka magazi, monga kudulidwa pang'ono pathupi, komwe kumatuluka magazi posachedwa.Koma thupi la munthu lidzadziteteza lokha.Pofuna kupewa kutaya magazi mpaka imfa, magazi amaundana pang'onopang'ono pamalo otaya magazi, ndiko kuti, magazi amapanga thrombus mumtsempha wamagazi wowonongeka.Mwanjira iyi, palibenso magazi.
Kutaya magazi kukasiya, thupi lathu limasungunula pang'onopang'ono thrombus, zomwe zimapangitsa kuti magazi aziyendanso.
Njira yomwe imapanga thrombus imatchedwa coagulation system;njira yomwe imachotsa thrombus imatchedwa fibrinolytic system.Mtsempha wamagazi ukawonongeka m'thupi la munthu, dongosolo la coagulation limatsegulidwa nthawi yomweyo kuti asapitirire magazi;pamene thrombus ichitika, dongosolo la fibrinolytic lomwe limachotsa thrombus lidzatsegulidwa kuti lisungunuke magazi.
Njira ziwirizi zimakhala zokhazikika, kuwonetsetsa kuti magazi samaundana kapena kutulutsa magazi kwambiri.
Komabe, matenda ambiri angayambitse kusokonezeka kwa dongosolo la coagulation, komanso kuwonongeka kwa intima ya mtsempha wamagazi, ndipo kukhazikika kwa magazi kumapangitsa dongosolo la fibrinolytic mochedwa kapena losakwanira kusungunula thrombus.
Mwachitsanzo, pachimake myocardial infarction, pali thrombosis mu mtima mitsempha ya magazi.Mitsempha yamagazi imakhala yosauka kwambiri, pali kuwonongeka kosiyanasiyana kwa intima, ndipo pali stenosis, kuphatikizapo kusayenda kwa magazi, palibe njira yothetsera thrombus, ndipo thrombus idzangokulirakulira.
Mwachitsanzo, mwa anthu omwe ali pabedi kwa nthawi yayitali, magazi a m'deralo amayenda pang'onopang'ono m'miyendo, intima ya mitsempha ya magazi imawonongeka, ndipo thrombus imapangidwa.The thrombus adzapitiriza kupasuka, koma Kutha liwiro si mofulumira mokwanira, akhoza kugwa, kuthamanga kubwerera mu mtsempha wa m`mapapo mwanga m`mapapo mtsempha wamagazi, kukakamira mu mtsempha wa m`mapapo mwanga, ndi chifukwa m`mapapo mwanga embolism, amenenso amapha.
Panthawi imeneyi, pofuna kuonetsetsa chitetezo cha odwala, m'pofunika kupanga thrombolysis ndi jekeseni mankhwala ntchito kulimbikitsa thrombolysis, monga "urokinase".Komabe, thrombolysis imafunika kuchitidwa pakanthawi kochepa, monga mkati mwa maola 6.Ngati zitenga nthawi yayitali, sizingasungunuke.Ngati muwonjezera kugwiritsa ntchito mankhwala a thrombolytic panthawiyi, kungayambitse magazi m'madera ena a thupi.
Thrombus sangathe kusungunuka.Ngati sichinatsekedwe kwathunthu, "stent" ingagwiritsidwe ntchito "kutsegula" mtsempha wotsekedwa kuti magazi aziyenda bwino.
Komabe, ngati chotengera chamagazi chatsekedwa kwa nthawi yayitali, chimayambitsa ischemic necrosis yamagulu ofunikira a minofu.Panthawi imeneyi, kokha mwa "kulambalala" mitsempha ina yamagazi ikhoza kuyambitsidwa "kuthirira" chidutswa cha minofu yomwe yataya magazi.
Magazi ndi coagulation, thrombosis ndi thrombolysis, ndi bwino bwino lomwe limasunga ntchito kagayidwe kachakudya m'thupi.Osati kokha, pali miyeso yambiri yanzeru m'thupi la munthu, monga mitsempha yachifundo ndi mitsempha ya vagus, yomwe imasunga chisangalalo cha anthu popanda kukhala okondwa kwambiri;insulin ndi glucagon amawongolera kuchuluka kwa shuga m'magazi a anthu;calcitonin ndi parathyroid hormone imayang'anira shuga wamagazi a anthu.
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