Matenda a coagulation ali pachiwopsezo cha moyo, chifukwa kusokonezeka kwa coagulation kumachitika pazifukwa zosiyanasiyana zomwe zimapangitsa kuti ntchito ya thupi la munthu iwonongeke.Pambuyo coagulation kukanika, thupi la munthu adzaoneka angapo zizindikiro magazi.Ngati kukha mwazi kwakukulu kwa intracranial kumachitika, ndizoopsa kwambiri.Chifukwa coagulation kukanika akhoza chifukwa cha matenda osiyanasiyana, matenda ambiri akusowa vitamini K, kufalitsidwa intravascular coagulation, aakulu chiwindi matenda, hemophilia a, hemophilia b, von Willebrand matenda, etc. Coagulation matenda akhoza kuchitika matenda.

Ngati ndi wodwala matenda a haemophilia A kwambiri, amakhala ndi chizolowezi chokhetsa magazi, ndipo ndikosavuta kutulutsa magazi pambuyo povulala pang'ono.Ngati wodwala matenda a haemophilia A akumana ndi zoopsa, zimakhala zosavuta kuyambitsa kukha magazi kwambiri muubongo, zomwe zimayika moyo wa wodwalayo pachiswe.Komanso, kwambiri kufalitsidwa intravascular coagulation nawonso sachedwa kwambiri magazi chifukwa kumwa zosiyanasiyana coagulation zinthu ndi coagulation kukanika, zikubweretsa imfa oyambirira odwala.