Kodi kuchuluka kwa D-dimer ndi koopsa bwanji?


Wolemba: Wolowa m'malo   

D-dimer ndi chinthu chowonongeka cha fibrin, chomwe nthawi zambiri chimagwiritsidwa ntchito poyesa ma coagulation.Mulingo wake wabwinobwino ndi 0-0.5mg/L.Kuwonjezeka kwa D-dimer kungakhale kokhudzana ndi zochitika za thupi monga mimba, kapena Zimakhudzana ndi zinthu za pathological monga matenda a thrombotic, matenda opatsirana, ndi zotupa zowopsa.Ndibwino kuti odwala apite ku dipatimenti ya hematology ya chipatala kuti akalandire chithandizo panthawi yake.

1. Zokhudza thupi:
Pa nthawi ya mimba, kuchuluka kwa mahomoni m'thupi kumasintha, zomwe zingayambitse kuwonongeka kwa fibrin kuti apange D-dimer, zomwe zingayambitse kuwonjezeka kwa D-dimer m'magazi, koma nthawi zambiri zimakhala mkati mwanthawi zonse kapena kuwonjezeka pang'ono. Ndizochitika zakuthupi ndipo nthawi zambiri sizifuna chithandizo chapadera.

2. Pathological zinthu:
1. Thrombotic matenda: Ngati pali thrombotic matenda m`thupi, monga deep mtsempha thrombosis, m`mapapo mwanga embolism, etc., izo zingachititse kuti magazi ntchito yachilendo, kupanga magazi mu hypercoagulable boma, ndi kulimbikitsa fibrinolytic dongosolo hyperactivity, kuchititsa D-dimerization Kuwonjezeka kwa zinthu zowonongeka kwa fibrin monga thupi ndi fibrin zina, zomwe zimapangitsa kuti D-dimer ichuluke m'magazi.Panthawiyi, motsogozedwa ndi dokotala, recombinant streptokinase ya jekeseni, urokinase ya jekeseni ndi mankhwala ena angagwiritsidwe ntchito pochiza kuti aletse mapangidwe a thrombus;

2. Matenda opatsirana: Ngati pali matenda aakulu m'thupi, monga sepsis, tizilombo toyambitsa matenda m'magazi timachulukana mofulumira m'thupi, kuwononga minofu ndi ziwalo za thupi lonse, kuwononga microvascular system, ndikupanga capillary thrombosis. m’thupi lonse.Zidzatsogolera kufalikira kwa intravascular coagulation m'thupi lonse, kulimbikitsa kupititsa patsogolo ntchito ya fibrinolytic m'thupi, ndikupangitsa kuchuluka kwa D-dimer m'magazi.Panthawiyi, wodwalayo amatha kugwiritsa ntchito mankhwala oletsa tizilombo toyambitsa matenda monga cefoperazone sodium ndi sulbactam sodium popanga jekeseni monga momwe adokotala adanenera.;

3. Zotupa zowopsa: Maselo owopsa a chotupa amamasula chinthu cha procoagulant, kulimbikitsa mapangidwe a thrombus m'mitsempha yamagazi, kenako ndikuyambitsa dongosolo la fibrinolytic, zomwe zimapangitsa kuti D-dimer ichuluke m'magazi.Panthawiyi, jakisoni wa paclitaxel, Chemotherapy ndi jakisoni wamankhwala monga cisplatin.Panthawi imodzimodziyo, mungathenso kuchita opaleshoni kuti muchotse chotupacho malinga ndi malangizo a dokotala, omwe amathandiza kuti matendawa ayambe kuchira.