Chiwindi ndi malo opangira zinthu zosiyanasiyana za coagulation, ndipo amatha kupanga ndikuyambitsa ma fibrin lysates ndi antifibrinolytics, ndikuchita nawo gawo lowongolera pakusunga mphamvu ya coagulation ndi anticoagulation system.Kuzindikira kwa zizindikiro zamagazi a magazi kwa odwala omwe ali ndi matenda a chiwindi a B kunasonyeza kuti panalibe kusiyana kwakukulu mu PTAPTT kwa odwala omwe ali ndi matenda a chiwindi B poyerekeza ndi gulu lolamulira (P> 0.05), koma panali kusiyana kwakukulu mu FIB (P<0.05) ).Panali kusiyana kwakukulu mu PT, APTT, ndi FIB pakati pa gulu lalikulu la hepatitis B ndi gulu lolamulira bwino (P<005P<0.01), zomwe zinatsimikizira kuti kuopsa kwa hepatitis B kunali kogwirizana bwino ndi kuchepa kwa magazi coagulation factor.

Kuwunikidwa kwa zifukwa zomwe zili pamwambazi:

1. Kupatulapo factor IV (Ca *) ndi cytoplasm, zinthu zina za plasma coagulation zimapangidwira m'chiwindi;anticoagulation factor (coagulation inhibitors) monga ATIPC, 2-MaI-AT, etc. amapangidwanso ndi chiwindi.kaphatikizidwe ka ma cell.Ma cell a chiwindi akawonongeka kapena necrotic ku madigiri osiyanasiyana, kuthekera kwa chiwindi kupanga zinthu zolumikizana ndi zinthu zotsutsana ndi coagulation kumachepetsedwa, ndipo milingo ya plasma yazinthu izi imachepetsedwanso, zomwe zimapangitsa kuti pakhale zopinga zamakina a coagulation.PT ndi kuyesa kuyesa kwa extrinsic coagulation system, yomwe ingasonyeze mlingo, ntchito ndi ntchito ya coagulation factor IV VX mu plasma.Kuchepetsa zomwe zili pamwambazi kapena kusintha kwa ntchito ndi ntchito zawo zakhala chimodzi mwa zifukwa za PT yaitali kwa odwala omwe ali ndi matenda a chiwindi chamtundu wa B ndi matenda aakulu a hepatitis B. Choncho, PT imagwiritsidwa ntchito kawirikawiri kuchipatala kuti iwonetsere kaphatikizidwe ka coagulation. zinthu m'chiwindi.

2. Komano, ndi kuwonongeka kwa maselo a chiwindi ndi kulephera kwa chiwindi kwa odwala matenda a hepatitis B, mlingo wa plasmin mu plasma ukuwonjezeka panthawiyi.Plasmin sangangotulutsa madzi ambiri a fibrin, fibrinogen ndi zinthu zambiri zophatikizika monga maphunziro a factor, XXX, VVII,Ⅱ, etc., komanso amadya zinthu zambiri zotsutsana ndi coagulation monga ATⅢPC ndi zina zotero.Chifukwa chake, ndikukula kwa matendawa, APTT idatalika ndipo FIB idatsika kwambiri mwa odwala a hepatitis B.

Pomaliza, kudziwika kwa coagulation indexes monga PTAPTTFIB ali ndi zofunika kwambiri zachipatala tanthauzo kuweruza chikhalidwe cha odwala matenda a chiwindi B, ndipo ndi tcheru ndi odalirika kudziwika index.