Nthawi ya Prothrombin (PT) imatanthawuza nthawi yofunikira kuti madzi a m'magazi atsekedwe pambuyo pa kusandulika kwa prothrombin kukhala thrombin pambuyo powonjezera minofu ya thromboplastin ndi kuchuluka koyenera kwa ayoni a calcium ku plasma yopanda magazi.Kuchuluka kwa prothrombin nthawi (PT), ndiko kuti, kutalika kwa nthawi, kungayambitsidwe ndi zifukwa zosiyanasiyana monga congenital abnormal coagulation factor, kupeza abnormal coagulation factor, abnormal blood anticoagulation status, etc. Kusanthula kwakukulu ndi motere:

1. Matenda a congenital coagulation factor: Kupanga kwachilendo kwa chimodzi mwazinthu zomwe zimaphatikizana ndi I, II, V, VII, ndi X m'thupi kumabweretsa nthawi yayitali ya prothrombin (PT).Odwala akhoza kuwonjezera coagulation zinthu motsogozedwa ndi madokotala kukonza izi;

2. Matenda opezeka ndi coagulation: matenda oopsa a chiwindi, kusowa kwa vitamini K, hyperfibrinolysis, kufalikira kwa intravascular coagulation, ndi zina zotero, izi zidzatsogolera kusowa kwa coagulation kwa odwala, zomwe zimapangitsa kuti prothrombin nthawi yayitali (PT).Zifukwa zenizeni ziyenera kudziwidwa kuti athandizidwe.Mwachitsanzo, odwala omwe ali ndi vuto la vitamini K akhoza kuthandizidwa ndi mtsempha wa vitamini K1 kuti apititse patsogolo kubwerera kwa prothrombin nthawi yabwino;

3. Kusakhazikika kwa magazi kwa anticoagulation: pali zinthu za anticoagulant m'magazi kapena wodwala amagwiritsa ntchito mankhwala oletsa magazi, monga aspirin ndi mankhwala ena, omwe ali ndi zotsatira za anticoagulant, zomwe zidzakhudza njira yowonongeka ndikutalikitsa nthawi ya prothrombin (PT).Ndibwino kuti odwala asiye mankhwala a anticoagulant motsogozedwa ndi madokotala ndikusintha njira zina zothandizira.

Nthawi ya Prothrombin (PT) yotalikirapo kuposa masekondi atatu imakhala ndi tanthauzo lachipatala.Ngati ndizokwera kwambiri ndipo sizikupitilira mtengo wabwinobwino kwa masekondi atatu, zitha kuwonedwa mosamalitsa, ndipo chithandizo chapadera sichifunikira.Ngati nthawi ya prothrombin (PT) italikirana kwa nthawi yayitali, ndikofunikira kuti mudziwe chomwe chimayambitsa ndikuchita chithandizo chomwe mukufuna.