N'zotheka kudziwa ngati wodwalayo ali ndi vuto la coagulation asanachite opaleshoni, kuteteza bwino zinthu zosayembekezereka monga kutuluka magazi osasiya panthawi ndi pambuyo pa opaleshoni, kuti apeze njira yabwino yopangira opaleshoni.
Ntchito ya hemostatic ya thupi imakwaniritsidwa ndi kuphatikizika kwa mapulateleti, ma coagulation system, fibrinolytic system ndi vascular endothelial system.M'mbuyomu, tinkagwiritsa ntchito nthawi yotaya magazi ngati kuyesa kuwunika kwa vuto la hemostatic, koma chifukwa cha kutsika kwake, kusamva bwino, komanso kulephera kuwonetsa zomwe zili ndi zochita za coagulation factor, m'malo mwake adasinthidwa ndi mayeso a coagulation.Mayesero a coagulation function makamaka amaphatikizapo plasma prothrombin time (PT) ndi PT ntchito yowerengedwa kuchokera ku PT, international normalized ratio (INR), fibrinogen (FIB), activated partial thromboplastin time (APTT) ndi plasma thrombin time (TT).
PT makamaka imasonyeza ntchito ya extrinsic coagulation system.Kutalika kwa PT kumawonekera makamaka mu congenital coagulation factor II, V, VII, ndi X kuchepetsa, kuchepa kwa fibrinogen, kupeza coagulation factor deficiency (DIC, primary hyperfibrinolysis, obstructive jaundice, kusowa kwa vitamini K, ndi anticoagulant zinthu m'magazi. makamaka congenital coagulation factor V kuwonjezeka, oyambirira DIC, thrombotic matenda, m`kamwa kulera, etc.; monitoring PT angagwiritsidwe ntchito ngati kuwunika matenda m`kamwa anticoagulant mankhwala.
APTT ndiye mayeso odalirika kwambiri owunika kuperewera kwa endogenous coagulation factor.APTT yotalikirapo imawonekera makamaka mu hemophilia, DIC, matenda a chiwindi, ndi kuthiridwa magazi ambiri osungidwa m'mabanki.APTT yofupikitsidwa imawoneka makamaka mu DIC, prothrombotic state, ndi matenda a thrombotic.APTT ingagwiritsidwe ntchito ngati chowunikira chamankhwala a heparin.
Kutalikitsa kwa TT kumawoneka mu hypofibrinogenemia ndi dysfibrinogenemia, kuwonjezeka kwa FDP m'magazi (DIC), ndi kukhalapo kwa heparin ndi zinthu za heparinoid m'magazi (mwachitsanzo, panthawi ya mankhwala a heparin, SLE, matenda a chiwindi, etc.).
Panali nthawi ina wodwala mwadzidzidzi amene analandira preoperative zasayansi mayesero, ndipo zotsatira za coagulation mayeso anali yaitali PT ndi APTT, ndi DIC ankakayikira wodwalayo.Pansi pa malingaliro a labotale, wodwalayo adayesedwa kangapo ka DIC ndipo zotsatira zake zinali zabwino.Palibe zizindikiro zoonekeratu za DIC.Ngati wodwala alibe coagulation mayeso, ndi opaleshoni mwachindunji, zotsatira zake zidzakhala zoopsa.Mavuto ambiri otere amatha kupezeka kuchokera ku mayeso a coagulation function, omwe agula nthawi yochulukirapo kuti azindikire komanso kuchiza matenda.Kuyesa kwa ma coagulation ndi mayeso ofunikira a labotale pakugwira ntchito kwa coagulation kwa odwala, komwe kumatha kuzindikira kukomoka kwapang'onopang'ono kwa odwala asanachite opaleshoni, ndipo kuyenera kulipidwa mokwanira.