Subcutaneous hemorrhage requires the following examinations:
1. Physical examination
The distribution of subcutaneous hemorrhage, whether the range of ecchymosis purpura and ecchymosis is higher than the surface of the skin, whether it fades, whether it is accompanied by itching and pain, whether there is gum bleeding, nasal bleeding, fever, and whether there are signs of anemia such as pale skin, nail bed, and sclera.
2. Laboratory examination
Including platelet count, blood count, bone marrow count, coagulation function, liver and kidney function, immunological examination, D-dimer, urine routine, stool routine, etc.
3. Imaging examination
X-ray, CT, magnetic resonance imaging (MRI), or PET/CT examination of bone lesions can assist in the diagnosis of myeloma patients with bone pain.
4. Pathological examination
Direct immunofluorescence examination of skin lesions and surrounding skin reveals deposition of vascular wall IgA, complement, and fibrin, which can be used to diagnose allergic purpura, etc.
5. Special inspection
The capillary fragility test can help diagnose the cause of subcutaneous hemorrhage by examining whether there is an increase in vascular fragility or damage to the vascular intima, as well as whether there are abnormalities in the quantity or quality of platelets.