PT means prothrombin time in medicine, and APTT means activated partial thromboplastin time in medicine. The blood coagulation function of the human body is very important. If the blood coagulation function is abnormal, it may lead to thrombosis or bleeding, which may seriously endanger the life of the patient. Clinical monitoring of PT and APTT values can be used as a standard for the use of some anticoagulant drugs in clinical practice. If the measured values are too high, it means that the dose of anticoagulant drugs needs to be reduced, otherwise bleeding will easily occur.

1. Prothrombin time (PT): It is one of the more sensitive indicators of the human blood coagulation system. It is more meaningful to prolong the time for more than 3 seconds in clinical practice, which can reflect whether the exogenous coagulation function is normal. Prolongation is generally seen in congenital coagulation Factor deficiency, severe cirrhosis, liver failure and other diseases. In addition, excessive doses of heparin and warfarin may also cause prolonged PT;

2. Activated partial thromboplastin time (APTT): It is mainly an index reflecting the endogenous blood coagulation function in clinical practice. Significant prolongation of APTT is mainly seen in congenital or acquired coagulation factor deficiency, such as hemophilia and systemic lupus erythematosus. If the dose of anticoagulant drugs used due to thrombosis is abnormal, it will also cause a significant prolongation of APTT. If the measured value is low, consider the patient to be in a hypercoagulable state, such as deep vein thrombosis.

If you want to know whether your PT and APTT are normal, you need to clarify their normal range. The normal range of PT is 11-14 seconds, and the normal range of APTT is 27-45 seconds. A PT prolongation of more than 3 seconds has greater clinical significance, and an APTT prolongation of more than 10 seconds has strong clinical significance.