1. Thrombocytopenia

Thrombocytopenia is a blood disorder that usually affects children. The amount of bone marrow production in patients with the disease will be reduced, and they are also prone to blood thinning problems, requiring long-term medication to control the disease.

Under the influence of thrombocytopenia, platelets are destroyed, leading to defects in platelet function. Therefore, platelets need to be supplemented in the process of continued deterioration of the disease, so that the coagulation function of the patient can be maintained.

2. Liver insufficiency

In clinical practice, hepatic insufficiency is also an important cause affecting coagulation function. Because coagulation factors and inhibitory proteins are synthesized in the liver, when the liver function is damaged, the synthesis of coagulation factors and inhibitory proteins will also be hindered accordingly, which will affect the coagulation function of patients.

For example, diseases such as hepatitis and liver cirrhosis will cause the body to have a certain degree of hemorrhagic complications, which are caused by the influence of the blood coagulation function when the liver function is damaged.

3. Anesthesia

Anesthesia may also cause problems with blood clotting. During surgery, anesthesia is usually used to assist in the completion of the surgery.

However, the use of anesthetic drugs can also adversely affect platelet function, such as inhibiting the release and aggregation of platelet particles.

In this case, the coagulation function of the patient will also malfunction, so it is very easy to cause coagulation dysfunction after the operation.

4. Blood thinning

So-called hemodilution refers to the infusion of large amounts of fluid into the body in a short period of time, in which the concentration of a substance in the blood decreases. When the blood is diluted, the coagulation system is activated, which can easily lead to thrombosis problems.

When the coagulation factor is consumed in large quantities, the normal coagulation function will be affected. Therefore, after the blood is diluted with food, it is also easy to cause coagulation failure.

5. Hemophilia

Hemophilia is a relatively common blood disorder whose main symptom is a malfunction of blood coagulation. Usually, the disease is mainly caused by inherited defects in clotting factors, so there is no complete cure.

When a patient has hemophilia, the original function of thrombin will be impaired, which will lead to serious bleeding problems, such as muscle bleeding, joint bleeding, visceral bleeding and so on.

6. Vitamin deficiency

When vitamin levels in the body are low, it can also cause problems with blood clotting. Because a variety of coagulation factors need to be synthesized together with vitamin K, these coagulation factors can have a very high dependence on vitamins.

Therefore, if there is a lack of vitamins in the body, there will be problems with the coagulation factors, and then the normal coagulation function cannot be maintained.
To sum up, there are many causes of coagulation dysfunction, so if patients blindly treat without knowing the specific cause, they will not only fail to improve their own conditions, but may even lead to more serious diseases.

Therefore, patients need to identify the specific reasons, and then start targeted treatment. Therefore, it is hoped that when there is a coagulation failure, you must go to a regular medical institution for examination, and carry out corresponding treatment according to the doctor's recommendation.