APTT is the English abbreviation of partially activated prothrombin time. APTT is a screening test reflecting the endogenous coagulation pathway. Prolonged APTT indicates that a certain blood coagulation factor involved in the human endogenous coagulation pathway is dysfunctional. After the APTT is prolonged, the patient will have obvious bleeding symptoms. For example, patients with hemophilia A, hemophilia B, and von Willebrand disease will all have prolonged APTT, and the patient will have ecchymosis on the skin and mucous membranes, and muscle bleeding. , joint bleeding, hematoma, etc. Especially for patients with hemophilia A, joint deformities and muscle atrophy are often left after the hematoma is absorbed due to synovitis caused by joint bleeding, which has a serious impact on health. In addition, disseminated intravascular coagulation, severe liver disease and other diseases will also cause significant prolongation of APTT, which will cause obvious harm to the human body.
A high value of Aptt indicates that the patient may suffer from bleeding disorders. Common bleeding disorders include congenital coagulation factor deficiency and hemophilia. Secondly, it is suspected to be caused by liver disease or obstructive jaundice or thrombotic disease. It is also not ruled out that it is caused by the influence of drug factors, such as long-term use of anticoagulant drugs. Clinically, the aptt test can be used to judge whether the coagulation function in the patient's body is normal. If it is due to the phenomenon caused by hemophilia, it is recommended to follow the doctor's advice to stop bleeding or use prothrombin complex treatment.