D-Dimer dynamic monitoring predicts VTE formation:
As mentioned earlier, the half-life of D-Dimer is 7-8 hours, which is precisely because of this characteristic that D-Dimer can dynamically monitor and predict VTE formation. For transient hypercoagulability or the formation of microthrombosis, D-Dimer will slightly increase and then rapidly decrease. When there is persistent fresh blood clot formation in the body, the D-Dimer in the body will continue to rise, presenting a peak like elevation curve. For patients with a high incidence of thrombosis, such as acute and severe cases, postoperative patients, etc., if there is a rapid increase in D-Dimer levels, it is necessary to be vigilant about the possibility of thrombosis. In the "Expert Consensus on the Screening and Treatment of Deep Venous Thrombosis in Traumatic Orthopedic Patients", it is recommended to dynamically observe changes in D-Dimer every 48 hours for moderate to high risk patients after orthopedic surgery. Patients with continuous positive or elevated D-Dimer should undergo imaging examination in a timely manner to identify DVT.