Blood coagulation is a normal protective mechanism in the body. If a local injury occurs, coagulation factors will quickly accumulate at this time, causing the blood to coagulate into a jelly-like blood clot and avoid excessive blood loss. If coagulation dysfunction, it will lead to excessive blood loss in the body. Therefore, when coagulation dysfunction is found, it is necessary to understand the reasons that may affect the coagulation function and treat it.

 

What is the cause of coagulation dysfunction?

1. Thrombocytopenia

Thrombocytopenia is a common blood disease that may occur in children. This disease can lead to reduced bone marrow production, excessive consumption, and blood dilution problems. Patients need long-term medication to control it. Because this disease can cause platelet destruction and also cause platelet function defects, when the patient's disease is more serious, it needs to be supplemented to help the patient maintain blood coagulation function.

2. Blood thinning

Hemodilution mainly refers to the infusion of a large amount of fluid in a short period of time. This situation will reduce the concentration of substances in the blood and easily activate the coagulation system. During this period, it is easy to cause thrombosis, but after a large amount of coagulation factors are consumed, it will Affects the normal coagulation function, so after blood dilution, coagulation dysfunction is more common.

3. Hemophilia

Hemophilia is a common blood disease. The problem of coagulopathy is the main symptom of hemophilia. This disease is caused by the defects of hereditary coagulation factors, so it cannot be completely cured. When this disease occurs, it will cause prothrombin dysfunction, and the bleeding problem will be relatively serious, which may cause muscle bleeding, joint bleeding and internal organ bleeding

4. vitamin deficiency

Vitamin deficiency is also likely to cause coagulation dysfunction, because a variety of coagulation factors need to be synthesized in the liver together with vitamin k. This part of the coagulation factor is called a vitamin k-dependent coagulation factor. Therefore, in the absence of vitamins, the coagulation factor will also be lacking and cannot fully participate in the coagulation function, resulting in coagulation dysfunction.

5. liver insufficiency

Hepatic insufficiency is a common clinical cause that affects coagulation function, because the liver is the main synthesis site of coagulation factors and inhibitory proteins. If liver function is insufficiency, the synthesis of coagulation factors and inhibitory proteins cannot be maintained, and it is in the liver. When the function is impaired, the patient's coagulation function will also change significantly. For example, diseases such as hepatitis, liver cirrhosis, and liver cancer can cause bleeding complications of varying degrees. This is the problem caused by liver function affecting blood coagulation.

 

Coagulation dysfunction can be caused by many reasons, so when coagulation dysfunction is found, you must go to the hospital for detailed examination to find out the specific cause and provide targeted treatment for the cause.