Coagulation factors and thrombin are not the same drug. They differ in composition, mechanism of action and scope of application, as follows:

Composition and properties
Coagulation factors: various protein components involved in the blood coagulation process, including coagulation factors Ⅰ (fibrinogen), Ⅱ (prothrombin), Ⅴ, Ⅶ, Ⅷ, Ⅸ, Ⅹ, Ⅺ, Ⅻ and other factors. Most of them are proteins synthesized in the liver and exist in the blood as inactive precursors.
Thrombin: a serine protease formed by the activation of prothrombin and a key enzyme in the coagulation cascade.

Mechanism of action
Coagulation factors: activated through a series of complex enzymatic reaction cascades, ultimately converting fibrinogen into fibrin to form a blood clot. Different coagulation factors play different roles in this process, for example, coagulation factors Ⅷ and Ⅸ participate in the intrinsic coagulation pathway, and coagulation factor Ⅶ participates in the exogenous coagulation pathway, etc.
Thrombin: directly acts on fibrinogen, cutting it into fibrin monomers, which then cross-link to form a stable fibrin network, causing blood to coagulate. At the same time, thrombin can also activate platelets, promote platelet aggregation, and further strengthen the coagulation process.

Scope of application
Coagulation factors: mainly used to treat bleeding diseases caused by coagulation factor deficiency, such as hemophilia A (coagulation factor VIII deficiency), hemophilia B (coagulation factor IX deficiency), and coagulation factor II, VII, IX, and X deficiency caused by vitamin K deficiency.
Thrombin: often used for local hemostasis, such as bleeding from surgical wounds and traumatic wounds, and can also be used for gastrointestinal bleeding, such as oral or local infusion to treat bleeding from gastric and duodenal ulcers.
Coagulation factors and thrombin both play an important role in the coagulation process, but they are different substances and their clinical applications are also different.

Beijing Succeeder Technology Inc. (Stock code: 688338), founded in 2003 and listed since 2020, is a leading manufacturer in coagulation diagnostics. We specialize in automated coagulation analyzers and reagents, ESR/HCT analyzers, and hemorheology analyzers. Our products are certified under ISO 13485 and CE, and we serve over 10,000 users worldwide.

Analyzer Introduction
Fully Automated Coagulation analyzer SF-9200 (https://www.succeeder.com/fully-automated-coagulation-analyzer-sf-9200-product) can be used for clinical test and pre-operative screening. Hospitals and medical scientific researchers also can use SF-9200. Which adopts coagulation and immunoturbidimetry, chromogenic method to test the clotting of plasma. The instrument shows that clotting measurement value is the clotting time (in seconds). If the test item is calibrated by calibration plasma, it can also display other related results.
The product is made of sampling probe movable unit, cleaning unit, cuvettes movable unit, heating and cooling unit, test unit, operation-displayed unit, LIS interface (used for printer and transfer date to Computer).
Technical and experienced staffs and analyzers of high quality and strict quality management are the guarantee of manufacture of SF-9200 and good quality. We guarantee each instrument inspected and tested strictly. SF-9200 meets China national standard, industry standard, enterprise standard and IEC standard.