I raro i nga ahuatanga o te tinana, ko nga punaha e rua o te whakaheke toto me te anticoagulation i roto i te tinana kei te pupuri i te toenga hihiri ki te pupuri i te toto e rere ana i roto i nga oko toto.Mena kaore i te taurite te pauna, ko te punaha anticoagulation te nuinga me te kaha o te whakaheke toto ka puta, ka kaha te punaha coagulation me te thrombosis ka puta.Ko te punaha fibrinolysis he waahi nui ki te thrombolysis.I tenei ra ka korero tatou mo etahi atu tohu e rua o te punaha fibrinolysis, D-dimer me FDP, kia tino mohio ki te hemostasis i hangaia e te thrombin ki te thrombus i timatahia e te fibrinolysis.Whakawhanaketanga.Whakaratohia nga korero taketake haumanu e pa ana ki te thrombosis me te mahi coagulation.
Ko te D-dimer he hua whakakino motuhake i hangaia e te monomer fibrin i hono-whakawhitihia e te tauwehe XIII kua whakahohehia, katahi ka whakamarohia e te plasmin.Ko te D-dimer i ahu mai i te kopa fibrin hono-whakawhiti kua whakakorehia e te plasmin.Ko te D-dimer teitei e tohu ana i te aroaro o te hyperfibrinolysis tuarua (penei i te DIC).Ko te FDP te kupu whanui mo nga hua whakaheke i puta i muri i te pakaru o te fibrin, te fibrinogen ranei i raro i te mahi a te plasmin i puta i te hyperfibrinolysis.Kei roto i te FDP nga hua fibrinogen (Fg) me te monomer fibrin (FM) (FgDPs), me nga hua whakaheke fibrin hono-whakawhiti (FbDPs), kei roto i nga FbDP nga D-dimer me etahi atu kongakonga, ka piki ake o raatau taumata. Ko te mahi fibrinolytic he hyperactive (fibrinolysis tuatahi, fibrinolysis tuarua ranei)
【Tauira】
I whakauruhia he tane takawaenga ki te hohipera a ko nga hua o te tirotiro toto e whai ake nei:
| Tūemi | Hua | Awhe Tohutoro |
| PT | 13.2 | 10-14s |
| APTT | 28.7 | 22-32s |
| TT | 15.4 | 14-21s |
| FIB | 3.2 | 1.8-3.5g/l |
| DD | 40.82 | 0-0.55mg/I FEU |
| FDP | 3.8 | 0-5mg/l |
| AT-III | 112 | 75-125% |
Ko nga mea e wha o te coagulation he kino katoa, he pai te D-dimer, he kino te FDP, he rereke nga hua.I te tuatahi i whakapaehia he paanga matau, i tirohia ano te tauira e te maha me te whakamatautau waimeha 1:10, ko te hua e whai ake nei:
| Tūemi | Taketake | 1:10 waimeha | Awhe Tohutoro |
| DD | 38.45 | 11.12 | 0-0.55mg/I FEU |
| FDP | 3.4 | Kei raro i te rohe o raro | 0-5mg/l |
Ka kitea mai i te waimehatanga ko te hua o te FDP he mea noa, a, ko te D-dimer kaore i te raina i muri i te dilution, ka whakapaehia te pokanoa.Waiho te hemolysis, lipemia, me te jaundice mai i te mana o te tauira.Na nga hua koretake o te waimeha, ka puta pea enei keehi i roto i te pokanoa noa ki nga paturopi heterophilic me nga mea rūmatoid.Tirohia te hītori hauora o te tūroro me te rapu i te hitori o te mate rūmātiki.Te taiwhanga Ko te hua o te whakamätautau take RF i tino nui.I muri i te korero ki te whare haumanu, ka korerohia te manawanui me te tuku korero.I te whai i muri mai, karekau he tohu e pa ana ki te thrombus, a, i whakatauhia he keehi pai mo D-dimer.
【Whakarāpopoto】
Ko te D-dimer he tohu nui mo te whakakore kino o te thrombosis.He nui te tairongo, engari ka ngoikore te motuhake.He waahanga ano o nga hua pai teka.Ko te whakakotahitanga o te D-dimer me te FDP ka taea te whakaiti i tetahi waahanga o te D- Mo te pai teka o te dimer, ka whakaatu te hua taiwhanga ko D-dimer ≥ FDP, ka taea te whakatau i nga whakatau e whai ake nei mo te hua whakamatautau:
1. Mena he iti nga uara (
2. Mēnā he uara nui te hua (>Uara tapahi), tātarihia ngā āhuatanga whakaawe, tērā pea he āhuatanga pokanoa.E taunaki ana kia mahia he whakamatautau waimeha maha.Mena he raina te hua, ka nui ake te pai o te pono.Mena karekau he raina, he hua teka.Ka taea hoki e koe te whakamahi i te reagent tuarua mo te manatoko me te korero ki te whare haumanu i te waa.
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