Ko te whakatau kaore i te pai te mahi whakaheke toto ka whakatauhia e te ahuatanga o te toto, me nga whakamatautau taiwhanga.Ko te nuinga o nga waahanga e rua, ko tetahi he toto ohorere, ko tetahi kei te whakaheke toto i muri i te whara, i te pokanga ranei.

Kaore i te pai te mahi o te coagulation, ara, he raruraru ki te take coagulation, kua heke te tau, he rereke ranei te mahi, a ka puta he raupapa o nga tohu whakaheke toto.Ka puta te toto ohorere, ka kitea te purpura, te ecchymosis, te epistaxis, te toto kapia, te hemoptysis, te hematemesis, te hematochezia, te hematuria, me etahi atu i roto i te kiri me nga kiri mucous.I muri i te whara, i te pokanga ranei, ka piki ake te nui o te toto, ka roa te wa whakaheke toto.

Na roto i te tirotiro i te wa prothrombin, te wa prothrombin kua whakahohehia, te wa thrombin, te kukū fibrinogen me etahi atu mea, ka taea te tirotirohia kaore i te pai te mahi o te coagulation, a me tohu te take motuhake.