1. Ko te Plasma D-dimer assay he whakamatautau kia mohio ai koe ki te mahi fibrinolytic tuarua.
Tikanga tirotiro: Ko te anti-DD monoclonal antibody kua pania ki nga matūriki latex.Mena he D-dimer kei roto i te plasma receptor, ka puta te tauhohenga antigen-antibody, ka whakahiato nga matūriki taherapa.Heoi ano, he pai tenei whakamatautau mo nga toto e pa ana ki te hanganga o te toto, no reira he iti te motuhake me te nui o te tairongo.
2. E rua nga puna o D-dimer in vivo
(1) Te ahua o te hypercoagulable me te hyperfibrinolysis tuarua;
(2) thrombolysis;
Ko te D-dimer te nuinga e whakaatu ana i te mahi fibrinolytic.Ka piki ake, he pai ranei ka kitea i roto i te hyperfibrinolysis tuarua, penei i te ahua o te hypercoagulable, te tohatoha intravascular coagulation, te mate renal, te whakakore i te okana, te rongoa thrombolytic, etc.
3. I te mea he kaha te thrombosis me te mahi fibrinolytic i roto i nga oko toto o te tinana, ka piki ake te D-dimer.
Hei tauira: te mate o te ngakau, te mate o te roro, te embolism pulmonary, te thrombosis venous, te pokanga, te puku, te whakahiato i roto i nga oko toto, te mate me te necrosis kiko ka nui ake te D-dimer.Ina koa mo nga kaumatua me nga turoro i roto i te hohipera, na te huakita me etahi atu mate, he ngawari ki te whakaheke toto toto me te arahi ki te piki D-dimer.
4. Ko te tohu motuhake e whakaatuhia ana e D-dimer kaore e pa ana ki te mahi i roto i tetahi mate motuhake, engari ki nga ahuatanga pathological noa o tenei roopu nui o nga mate me te coagulation me te fibrinolysis.
Ko te tikanga, ko te hanga o te fibrin honohono he thrombosis.Heoi, he maha nga mate haumanu ka taea te whakahohe i te punaha coagulation i te wa e tupu ana me te whanaketanga o te mate.I te wa e whakaputahia ai te fibrin hono-whakawhitinga, ka whakahohehia te punaha fibrinolytic, ka whakamarohia te fibrin hono-whakawhiti ki te aukati i tana "whakaemi" nui.(he thrombus tino haumanu), ka hua ake te D-dimer.No reira, ko te D-dimer teitei ehara i te mea he thrombosis tino haumanu.Mo etahi mate, tangata takitahi ranei, he tukanga pathological pea.