Hemostasis nke anụ ahụ bụ otu n'ime usoro nchebe dị mkpa nke ahụ.Mgbe arịa ọbara mebiri emebi, n'otu aka ahụ, a chọrọ ka ọ mepụta plọg hemostatic ngwa ngwa iji zere ịnwụ ọbara;N'aka nke ọzọ, ọ dị mkpa iji belata nzaghachi hemostatic na akụkụ ahụ mebiri emebi ma nọgide na-enwe ọnọdụ mmiri nke ọbara n'ime arịa ọbara usoro.Ya mere, hemostasis physiological bụ ihe dị iche iche nke ihe na usoro na-emekọrịta ihe iji nọgide na-enwe nguzozi ziri ezi.N'ụlọ ọgwụ, a na-ejikarị obere agịga na-akụ ntị ma ọ bụ mkpịsị aka iji mee ka ọbara na-asọpụta n'onwe ya, wee tụọ ogologo oge ọbara ọgbụgba.A na-akpọ oge a oge ọbara ọgbụgba (oge ọbara ọgbụgba), na ndị nkịtị anaghị agafe nkeji 9 (usoro ihe atụ).Ogologo oge ọbara ọgbụgba nwere ike igosipụta ọnọdụ ọrụ hemostatic physiological.Mgbe ọrụ hemostatic physiological na-ebelata, ọbara ọgbụgba na-emekarị, na ọrịa hemorrhagic na-eme;ebe imebiga ihe ókè nke ọrụ hemostatic physiological nwere ike ibute thrombosis pathological.

Isi usoro nke physiological hemostasis
Usoro hemostasis physiological na-agụnye usoro atọ: vasoconstriction, platelet thrombus formation na coagulation ọbara.

1 Vasoconstriction Physiological hemostasis na-ebu ụzọ pụta dị ka mkpirisi nke arịa ọbara mebiri emebi na obere arịa ọbara dị nso, nke na-ebelata ọbara ọgbụgba mpaghara ma bara uru iji belata ma ọ bụ gbochie ọbara ọgbụgba.Ihe na-akpata vasoconstriction gụnyere akụkụ atọ ndị a: ① mmerụ ahụ na-akpali akpali reflex na-akpata vasoconstriction;② Mmebi na mgbidi vaskụla na-akpata mkpụkọ myogenic vaskụla mpaghara;③ Platelet na-arapara na mmerụ ahụ na-ahapụ 5-HT, TXA₂, wdg iji kpachie arịa ọbara.ihe na-akpata vasoconstriction.

2 Nhazi nke thrombus nke nwere amamihe nke platelet Mgbe mmerụ ahụ arịa ọbara gasịrị, n'ihi mkpughe nke subendothelial collagen, obere obere platelet na-arapara na subendothelial collagen n'ime 1-2 sekọnd, nke bụ nzọụkwụ mbụ na nhazi nke hemostatic thrombus.Site na nrachi nke platelet, enwere ike "ịmata ebe mmerụ ahụ", nke mere na nkwụnye hemostatic nwere ike idobe ya nke ọma.platelet na-agbakwunyere na-eme ka ụzọ mgbaàmà platelet rụọ ọrụ iji mee ka platelet rụọ ọrụ ma hapụ ADP na TXA₂ endogenous, nke na-eme ka platelet ndị ọzọ dị n'ọbara, na-ewebata platelet ndị ọzọ ka ha na-arapara n'ahụ ibe ha ma na-akpata nchịkọta na-enweghị ike ịgbanwe;Mkpụrụ ndụ ọbara uhie mebiri emebi na-ahapụ ADP na mpaghara thrombin nke a na-emepụta n'oge usoro nhazi ahụ nwere ike ime ka platelet ndị na-asọba n'akụkụ ọnya ahụ na-aga n'ihu ma na-agbakọta na platelet ndị ejirila ma tinye ya na subendothelial collagen, ma mesịa mepụta platelet hemostatic plọg. gbochie ọnya ahụ wee nweta hemostasis nke mbụ, nke a makwaara dị ka hemostasis nke mbụ (irsthemostasis).Hemostasis nke mbụ dabere na vasoconstriction na nguzobe nke plọg hemostatic platelet.Na mgbakwunye, mbelata nke PGI₂ na NO mmepụta na endothelium vaskụla mebiri emebi na-abakwa uru na nchịkọta platelet.

3 Mkpokọta ọbara nke arịa ọbara mebiri emebi nwekwara ike ime ka sistemu coagulation ọbara rụọ ọrụ, nchikota ọbara nke mpaghara na-apụta ngwa ngwa, nke na fibrinogen soluble na plasma na-agbanwe ka ọ bụrụ fibrin na-adịghị ike, wee kenye ya na netwọk iji mee ka plọg hemostatic siri ike, nke a na-akpọ nke abụọ. hemostasis (hemostasis nke abụọ) hemostasis) (Fig 3-6).N'ikpeazụ, anụ ahụ fibrous dị n'ógbè ahụ na-amụba ma na-etolite n'ime mkpụkọ ọbara iji nweta hemostasis na-adịgide adịgide.

A na-ekewa hemostasis physiological ụzọ atọ: vasoconstriction, platelet thrombus formation, na coagulation ọbara, ma usoro atọ ndị a na-eme n'otu n'otu ma na-ejikọta ibe ha, ma na-ejikọta ibe ha.Platelet adhesion dị mfe iji nweta naanị mgbe ọbara na-ebelata site na vasoconstriction;S-HT na TXA2 ewepụtara mgbe arụ ọrụ platelet nwere ike ịkwalite vasoconstriction.platelet arụ ọrụ na-enye elu phospholipid maka ịgbalite ihe coagulation n'oge coagulation ọbara.Enwere ọtụtụ ihe na-akpata coagulation n'elu platelet, na platelet nwekwara ike ịhapụ ihe ndị na-akpata coagulation dị ka fibrinogen, si otú ahụ na-eme ka usoro coagulation dịkwuo ngwa ngwa.thrombin a na-emepụta n'oge coagulation ọbara nwere ike ime ka ọrụ platelet dị ike.Na mgbakwunye, mkpụkọ nke platelet n'ime mkpụkọ ọbara nwere ike ime ka mkpụkọ ọbara ahụ laghachi azụ wee wepụ serum dị na ya, na-eme ka mkpụkọ ọbara ahụ sie ike ma mechie oghere nke arịa ọbara.Ya mere, usoro atọ nke hemostasis physiological na-akwalite ibe ha, nke mere na e nwere ike ime usoro hemostasis physiological n'oge na ngwa ngwa.N'ihi na platelet nwere njikọ chiri anya na njikọ atọ dị na usoro hemostasis physiological, platelet na-arụ ọrụ dị oke mkpa na usoro hemostasis physiological.A na-agbatị oge ọbara ọgbụgba mgbe platelet belatara ma ọ bụ belata ọrụ ya.