Thrombin nwere ike ịkwalite coagulation ọbara, na-ekere òkè n'ịkwụsị ọbara ọgbụgba, ma nwee ike ịkwalite ọgwụgwọ ọnya na nrụzi anụ ahụ.

Thrombin bụ ihe dị mkpa enzyme na usoro nke coagulation ọbara, na ọ bụ isi enzyme na mbụ ghọrọ fibrin na fibrin.Mgbe arịa ọbara mebiri emebi, a na-emepụta glycrase n'okpuru ọrụ platelet na sel endothelial vaskụla, na-akwalite agglomeration platelet na thrombosis, si otú ahụ kwụsị hemostasis.Na mgbakwunye, nhazi nwekwara ike ịkwalite ọgwụgwọ ọnya na nrụzi anụ ahụ, nke bụ ihe dị mkpa enzyme dị mkpa na nrụzi anụ ahụ.

Ekwesiri iburu n'uche na oke ịgbalite thrombin nwekwara ike ibute nsogbu dika thrombosis na ọrịa obi.Ya mere, ọ dị mkpa ịgbaso ndụmọdụ dọkịta na usoro ọgwụgwọ mgbe ị na-eji ọgwụ ndị na-ejikọta ọnụ iji zere mmeghachi omume ọjọọ na mmetụta ndị ọzọ.

Ọrụ fibrinogen bụ na mbụ mmetụta nke ịkwalite platelet agglomeration na coagulation ọbara.Fibrinogen bụbu protein dị mkpa na usoro nke coagulation.Isi ọrụ ya bụ coagulation na hemostasis, na ikere òkè na mmepụta nke platelet.Uru nkịtị nke fibrinogen bụ 2-4g / L.Mmụba nke ọkwa mbụ nke fibrin nwere njikọ chiri anya na omume nke ọrịa thrombotic.ịrị elu nke fibrin nwere ike ịbụ ihe kpatara physiological, dị ka ime ime n'oge na afọ, ma ọ bụ ihe ndị na-akpata ọrịa, dị ka ọbara mgbali elu, ọrịa shuga, ọrịa obi atherosclerotic nke akwara obi.

Ọkwa fibrin na-ebelata, nke nwere ike ibute ọrịa imeju, dị ka cirrhosis na nnukwu ịba ọcha n'anya.Ndị ọrịa kwesịrị ịga ụlọ ọgwụ maka nyocha n'oge ma gwọọ ha n'okpuru nduzi nke dọkịta.