Thrombosis na hemostasis bụ ọrụ physiological dị mkpa nke ahụ mmadụ, gụnyere arịa ọbara, platelet, ihe na-akpata coagulation, protein anticoagulant, na sistem fibrinolytic.Ha bụ usoro usoro ziri ezi nke na-eme ka oruru ọbara na-eru n'ahụ mmadụ anya.Na-aga n'ihu na-ekesa mmiri na-aga n'ihu, ọ bụghị na-esi na arịa ọbara pụta (hemorrhage) ma ọ bụ coagulation na arịa ọbara (thrombosis).

A na-ekewa usoro nke thrombosis na hemostasis n'ime usoro atọ:

Hemostasis nke mbụ na-etinye aka na mgbidi arịa, sel endothelial, na platelet.Mgbe arịa merụrụ ahụ, platelet na-agbakọta ngwa ngwa iji kwụsị ọbara ọgbụgba.

Hemostasis nke abụọ, nke a makwaara dị ka hemostasis plasma, na-eme ka sistemu coagulation rụọ ọrụ iji gbanwee fibrinogen ka ọ bụrụ fibrin na-ejikọtaghị ọnụ, nke na-etolite nnukwu mkpụkọ.

Fibrinolysis, nke na-agbaji fibrin mkpụkọ ma na-eweghachi usoro ọbara nkịtị.

A na-ahazi usoro ọ bụla nke ọma iji kwado ọnọdụ nguzozi.Mmebi na njikọ ọ bụla ga-eduga na ọrịa ndị metụtara ya.

Nsogbu ọbara ọgbụgba bụ okwu n'ozuzu maka ọrịa nke usoro hemostasis na-adịghị mma kpatara.Enwere ike kewaa nsogbu ọbara ọgbụgba ụzọ abụọ: ihe nketa na nke enwetara, na ngosipụta ụlọ ọgwụ na-abụkarị ọbara ọgbụgba n'akụkụ dị iche iche.Ọrịa ọgbụgba ọbara na-ahụ maka afọ, hemophilia A na-ahụkarị (erughị eru coagulation factor VIII), hemophilia B (erughị nke coagulation factor IX) na coagulation abnormalities nke na-akpata ụkọ fibrinogen;nsogbu ọbara ọgbụgba enwetara, nke a na-ahụkarị Enwere vitamin K na-adabere na ụkọ coagulation factor, ihe na-adịghị mma nke ọrịa imeju kpatara, wdg.

A na-ekekarị ọrịa thromboembolism n'ime akwara akwara na thromboembolism venous (venousthromboembolism, VTE).Ọkpụkpụ akwara na-adịkarị na akwara akwara, akwara ụbụrụ, akwara mesenteric, na akwara ụkwụ, wdg. Mmalite na-abụkarị na mberede, oke mgbu mpaghara nwere ike ime, dị ka angina pectoris, mgbu afọ, oke mgbu n'akụkụ aka, wdg. ;a na-akpata ya site na ischemia anụ ahụ na hypoxia na akụkụ ndị dị mkpa na-enye ọbara akụkụ ahụ na-adịghị mma, nhazi anụ ahụ na ọrụ, dị ka infarction myocardial, nkụda mmụọ obi, ujo cardiogenic, arrhythmia, ọgba aghara nke nsụhọ na hemiplegia, wdg;thrombus n'ịwụfu na-akpata ụbụrụ ụbụrụ ụbụrụ, ụbụrụ renal embolism, splenic embolism na mgbaàmà na akara ndị ọzọ metụtara ya.venous thrombosis bụ ụdị thrombosis miri emi na-ahụkarị na nsọtụ ala.Ọ na-adịkarị na akwara miri emi dị ka vein popliteal, vein femoral vein, vein mesenteric, na vein portal.Ngosipụta mmetụta uche bụ ọzịza mpaghara na ọkpụrụkpụ na-ekwekọghị ekwekọ nke nsọtụ ala.Thromboembolism na-ezo aka na mwepu nke thrombus site na ebe e guzobere, akụkụ ma ọ bụ kpamkpam na-egbochi ụfọdụ arịa ọbara n'oge usoro nke na-aga n'ihu na ọbara, na-akpata ischemia, hypoxia, necrosis (thrombosis arterial) na nkwụsịtụ, edema (usoro pathological nke venous thrombosis). .Mgbe thrombosis miri emi nke akụkụ dị ala daa, ọ nwere ike ịbanye na akwara pulmonary na mgbasa ọbara, ihe mgbaàmà na ihe ịrịba ama nke embolism pulmonary na-apụta.Ya mere, mgbochi nke venous thromboembolism dị mkpa karịsịa.