A na-ebutekarị thrombosis site na mmebi nke mkpụrụ ndụ endothelial nke obi, ọnọdụ ọbara na-adịghị mma, yana mmụba nke coagulation ọbara.

1. Cardiovascular endothelial cell mmerụ: Vascular endothelial cell mmerụ bụ ihe kasị mkpa na nkịtị na-akpata thrombus e guzobere, nke na-emekarị na rheumatic na infective endocarditis, oké atherosclerotic plaque ọnyá afọ, traumatic ma ọ bụ mkpali ngagharị Venous mmerụ saịtị, wdg Na mgbakwunye, Mgbe hypoxia, ujo, sepsis na nje endotoxin na-akpata mbibi endothelial buru ibu n'ime ahụ niile, collagen n'okpuru endothelium na-eme ka usoro coagulation ahụ rụọ ọrụ, na-ebute mgbasa nke intravascular coagulation, na thrombus na-etolite na microcirculation nke ahụ dum.

2. Ọnọdụ ọbara na-adịghị mma: tumadi na-ezo aka na mbelata nke ọbara na-agba ọsọ na ọgbọ nke eddies n'ime ọbara, wdg. Ihe ndị na-arụ ọrụ coagulation na thrombin na-erute ntinye uche achọrọ maka coagulation na mpaghara mpaghara, nke na-enyere aka nhazi nke thrombus.N'ime ha, veins na-adịkarị mfe na thrombus, bụ nke na-adịkarị na ndị ọrịa nwere nkụda mmụọ, ọrịa na-adịghị ala ala na ezumike ụra mgbe ọ gasịrị.Na mgbakwunye, ọbara na-eru n'obi na akwara na-adị ngwa ngwa, ọ dịghịkwa mfe ịmepụta thrombus.Otú ọ dị, mgbe ọbara na-eru na atrium aka ekpe, aneurysm, ma ọ bụ alaka nke arịa ọbara na-adị nwayọọ ma na-eme ugbu a n'oge mitral valve stenosis, ọ na-adịkarị mfe thrombosis.

3. Mmụba coagulation ọbara: N'ozuzu, mmụba nke platelet na coagulation ihe n'ime ọbara, ma ọ bụ mbelata nke ọrụ nke fibrinolytic usoro, na-eduga na hypercoagulable ọnọdụ n'ime ọbara, nke na-adịkarị na eketa na enweta hypercoagulable steeti.

Na mgbakwunye, nloghachi ọbara venous na-adịghị mma nwekwara ike ịkpata ya.Dị ka nchọpụta dị irè nke ọrịa nke onwe ya si dị, enwere ike nweta mgbochi na ọgwụgwọ sayensị ezubere iche iji nyere aka mgbake ahụike.