FIB bụ mbiri nke bekee maka fibrinogen, na fibrinogen bụ ihe na-akpata coagulation.Ọnụ ọgụgụ FIB coagulation ọbara dị elu pụtara na ọbara dị n'ọnọdụ hypercoagulable, na thrombus na-etolite ngwa ngwa.
Mgbe emechara usoro coagulation nke mmadụ, fibrinogen na-aghọ fibrin monomer n'okpuru ọrụ nke thrombin, na fibrin monomer nwere ike ịgbakọta n'ime fibrin polymer, nke na-enyere aka n'ịmepụta mkpụkọ ọbara ma na-arụ ọrụ dị mkpa na usoro nchịkọta coagulation.
Fibrinogen bụ nke hepatocytes na-emepụta nke ọma ma bụrụ protein nwere ọrụ coagulation.Ya nkịtị uru bụ n'etiti 2 ~ 4qL.Fibrinogen bụ ihe metụtara coagulation, mmụba ya na-abụkarị mmeghachi omume na-abụghị nke anụ ahụ ma bụrụ ihe dị ize ndụ maka ọrịa ndị metụtara thromboembolism.
Coagulation FIB uru nwere ike ịba ụba n'ọtụtụ ọrịa, mkpụrụ ndụ ihe nketa nkịtị ma ọ bụ ihe mkpali, lipids ọbara dị elu, ọbara mgbali elu.
Ọrịa obi dị elu, ọrịa obi, ọrịa shuga, ụkwara nta, ọrịa anụ ahụ jikọtara, ọrịa obi, na etuto ọjọọ.mgbe ị na-ata ahụhụ site na ọrịa niile dị n'elu nwere ike iduga n'ọgba aghara ọbara.Ya mere, ọnụ ọgụgụ FIB coagulation ọbara dị elu na-ezo aka na ọnọdụ nke ọbara ọbara dị elu.
Ọkwa fibrinogen dị elu pụtara na ọbara nọ n'ọnọdụ hypercoagulability na ọ na-enwekarị thrombosis.A na-akpọkwa Fibrinogen dị ka coagulation factor I. Ma ọ bụ coagulation endogenous ma ọ bụ exogenous coagulation, nzọụkwụ ikpeazụ nke fibrinogen ga-arụ ọrụ fibroblasts.A na-eji nwayọọ nwayọọ na-ejikọta protein na netwọk iji mepụta mkpụkọ ọbara, ya mere fibrinogen na-anọchite anya arụmọrụ nke coagulation ọbara.
Fibrinogen bụ nke imeju na-emepụta nke ọma ma nwee ike ibuli elu n'ọtụtụ ọrịa.Ihe ndị na-akpata mkpụrụ ndụ ihe nketa ma ọ bụ mkpasu iwe na-agụnye oke ọbara lipids, ọbara mgbali elu, ọrịa obi obi, ọrịa shuga, ụkwara nta, ọrịa anụ ahụ jikọtara, ọrịa obi, na Tumors ọjọọ ga-ebili.Mgbe nnukwu ịwa ahụ gasịrị, n'ihi na ahụ kwesịrị ịrụ ọrụ hemostasis, ọ ga-akpalikwa mmụba nke fibrinogen maka ọrụ hemostasis.
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