A na-enweta D-dimer site na eriri fibrin jikọtara ya na plasmin gbazere.Ọ na-egosipụtakarị ọrụ lytic nke fibrin.A na-ejikarị ya na nchọpụta nke venous thromboembolism, thrombosis miri emi na pulmonary embolism na ụlọ ọgwụ.Nnwale qualitative D-dimer adịghị mma, ma ọ bụrụ na ule ọnụọgụ kwesịrị ịbụ ihe na-erughị 200μg/L.

A na-ahụkarị D-dimer ma ọ bụ nsonaazụ ule dị mma na ọrịa ndị metụtara hyperfibrinolysis nke abụọ, dị ka ọnọdụ hypercoagulable, mgbasa ozi intravascular, ọrịa gbasara akụrụ, ịjụ transplant akụkụ, na ọgwụgwọ thrombolytic.Na mgbakwunye, mgbe thrombosis na-arụ ọrụ n'ime arịa ọbara nke anụ ahụ, ma ọ bụ ọrịa na-esonyere ọrụ fibrinolytic, D-dimer ga-abawanye nke ukwuu.Ọrịa ndị a na-ahụkarị dị ka myocardial infarction, pulmonary embolism, thrombosis miri emi nke akụkụ akụkụ akụkụ, ụbụrụ ụbụrụ, wdg;ọrịa ụfọdụ, ịwa ahụ, ọrịa tumor, na necrosis anụ ahụ na-ebutekwa D-dimer mụbaa;na mgbakwunye, ụfọdụ ọrịa autoimmune mmadụ, dị ka rheumatic endocarditis, ọrịa ogbu na nkwonkwo, lupus erythematosus systemic, wdg, nwekwara ike ime ka D-dimer mụbaa.

Na mgbakwunye na ịchọpụta ọrịa, nchọpụta ọnụọgụ nke D-dimer nwekwara ike igosipụta mmetụta thrombolytic nke ọgwụ na-eme n'ụlọ ọgwụ.Akụkụ nke ọrịa, wdg, na-enye aka.

N'ihe banyere D-dimer dị elu, ahụ nọ n'ihe ize ndụ dị ukwuu nke thrombosis.N'oge a, a ga-achọpụta ọrịa mbụ ozugbo enwere ike, a ga-amalitekwa usoro mgbochi thrombosis dịka akara DVT si dị.Enwere ike ịhọrọ ọgwụ ụfọdụ maka ọgwụgwọ mgbochi ọrịa, dị ka ntụtụ subcutaneous nke heparin calcium dị arọ ma ọ bụ rivaroxaban, nke nwere ụfọdụ mgbochi mgbochi na nguzobe nke thrombosis.Ndị nwere ọnya thrombotic kwesịrị ịmalite tumor thrombolytic ozugbo enwere ike n'ime oge ọla edo, ma nyochaa D-dimer kwa oge.