Ihe kpatara ya

1. Mmerụ ahụ nke endothelial nke obi
mmerụ ahụ endothelial vaskụla bụ ihe kachasị mkpa na nke na-emekarị na-akpata thrombus, ọ na-adịkarịkwa na rheumatic na ọrịa endocarditis, ọnya atherosclerotic plaque siri ike, traumatic ma ọ bụ mkpali arteriovenous mmerụ saịtị, wdg E nwekwara hypoxia, ujo, sepsis na nje bacteria. endotoxins nke na-ebute ọtụtụ ọrịa endogenous n'ime ahụ dum.
Mgbe mmerụ ahụ akpụkpọ ahụ gasịrị, collagen n'okpuru endothelium na-eme ka usoro coagulation ahụ rụọ ọrụ, na-eme ka coagulation intravascular gbasaa, na thrombus na-etolite na microcirculation nke ahụ dum.

2. Ọbara na-adịghị mma
Ọ na-ezo aka na mbelata nke ọbara na-agba ọsọ na ọgbọ nke eddies na-agba ọsọ ọbara, wdg, na ihe ndị na-eme ka coagulation na-arụ ọrụ na thrombin na-erute mkpokọta achọrọ maka coagulation na mpaghara mpaghara, nke na-eme ka e nwee thrombus.N'ime ha, veins na-adịkarị mfe na thrombus, bụ nke na-adịkarị na ndị ọrịa nwere nkụda mmụọ, ọrịa na-adịghị ala ala na ezumike ụra mgbe ọ gasịrị.Na mgbakwunye, ọbara na-eru n'obi na akwara na-adị ngwa ngwa, ọ dịghịkwa mfe ịmepụta thrombus.Otú ọ dị, mgbe ọbara na-eru na atrium aka ekpe, aneurysm, ma ọ bụ alaka nke arịa ọbara na-adị nwayọọ ma na-eme ugbu a n'oge mitral valve stenosis, ọ na-adịkarị mfe thrombosis.

3. Mmụba coagulation ọbara
Na mkpokọta, platelet na ihe coagulation na ọbara na-abawanye, ma ọ bụ ọrụ nke sistemu fibrinolytic na-ebelata, na-eduga n'ọnọdụ hypercoagulable n'ọbara, nke na-adịkarị na steeti eketa na enwetara hypercoagulable.

4. Ihe nketa hypercoagulable steeti
Ọ na-emetụta ihe nketa coagulation ihe ntụpọ, congenital ntụpọ nke protein C na protein S, wdg N'ime ha, kasị nkịtị ihe V gene mmụgharị, ọnụego mmụgharị nke mkpụrụ ndụ ihe nketa a nwere ike iru 60% na ndị ọrịa na-emegharị miri emi thrombosis.

5. Ọnọdụ hypercoagulable enwetara
A na-ahụkarị na ọrịa kansa pancreatic, ọrịa cancer akpa ume, ọrịa ara ara, ọrịa kansa prostate, ọrịa afọ afọ na etuto ahụ dị njọ nke metastatic, nke na-akpata ntọhapụ nke ihe ndị na-eme ihe na-eme ka mkpụrụ ndụ kansa pụta;ọ nwekwara ike ime na nnukwu trauma, nnukwu ọkụ ọkụ, nnukwu ịwa ahụ ma ọ bụ mgbe ọmụmụ nwa N'ihe omume nke oke ọbara na-efunahụ, na ọnọdụ ndị dị ka ọbara mgbali elu ime ime, hyperlipidemia, atherosclerosis nke akwara ọbara, ise siga, na oke ibu.