Kedu ihe bụ Anticoagulants Ọbara?

A na-akpọ reagents kemịkalụ ma ọ bụ ihe nwere ike igbochi coagulation ọbara, dị ka anticoagulants eke (heparin, hirudin, wdg), Ca2 + chelating agents (sodium citrate, potassium fluoride).Ihe mgbochi a na-ejikarị eme ihe gụnyere heparin, ethylenediaminetetraacetate (EDTA nnu), citrate, oxalate, wdg Na ngwa bara uru, a ga-ahọrọ ọgwụ mgbochi dịka mkpa dị iche iche iji nweta mmetụta dị mma.

Ọgwụgwọ Heparin

Ịgba ọgwụ Heparin bụ ọgwụ anticoagulant.A na-eji ya ebelata ikike nke ọbara imechi ma nyere aka gbochie mkpụkọ ndị na-emerụ ahụ ka ọ ghara ịmalite n'ime arịa ọbara.A na-akpọ ọgwụ a mgbe ụfọdụ ihe na-ebelata ọbara, ọ bụ ezie na ọ naghị eme ka ọbara dị nro.Heparin anaghị agbaze mkpụkọ ọbara nke etolitelarị, mana ọ nwere ike igbochi ha ibuwanye ibu, nke nwere ike ibute nnukwu nsogbu.

A na-eji Heparin egbochi ma ọ bụ gwọọ ụfọdụ ọrịa vaskụla, obi na ngụgụ.A na-ejikwa Heparin egbochi ịchịkọta ọbara n'oge ịwa ahụ emeghe, ịwa ahụ obi, dialysis akụrụ na mmịnye ọbara.A na-eji ya na obere doses iji gbochie thrombosis na ụfọdụ ndị ọrịa, karịsịa ndị a ga-eme ụdị ịwa ahụ ụfọdụ ma ọ bụ na-anọ n'elu akwa ruo ogologo oge.A pụkwara iji Heparin chọpụta ma gwọọ ọrịa ọbara siri ike nke a na-akpọsa coagulation intravascular.

Enwere ike zụta ya naanị site na ndenye ọgwụ dọkịta.

Nnu EDTC

Ihe kemịkal nke na-ejikọta ụfọdụ ion metal, dị ka calcium, magnesium, lead, na ígwè.A na-eji ọgwụ eme ihe iji gbochie ihe nlele ọbara ka ọ ghara imechi yana wepụ calcium na lead n'ime ahụ.A na-ejikwa ya iji gbochie nje bacteria na-emepụta biofilms (obere n'ígwé jikọtara n'elu).Ọ bụ onye na-ere ere.A na-akpọkwa ethylene diacetic acid na ethylene diethylenediamine tetraacetic acid.

EDTA-K2 nke International Hematology Standardization Committee tụrụ aro nwere ihe solubility kachasị elu yana ọsọ mgbochi mgbochi ngwa ngwa.