D-dimer dị elu ọ pụtara thrombosis?


Onye edemede: Onye nọchiri   

1. Plasma D-dimer assay bụ nyocha iji ghọta ọrụ fibrinolytic nke abụọ.

Ụkpụrụ nyocha: Anti-DD monoclonal antibody na-ekpuchi n'elu akụkụ latex.Ọ bụrụ na enwere D-dimer na plasma onye na-anabata ya, mmeghachi omume antigen-antibody ga-eme, ụmụ irighiri ihe latex ga-agbakọta.Agbanyeghị, ule a nwere ike ịdị mma maka ọbara ọgbụgba ọ bụla nwere mkpụkọ ọbara, yabụ na ọ nwere nkọwa dị ala na nghọta dị elu.

2. Enwere ụzọ abụọ nke D-dimer na vivo

(1) Hypercoagulable steeti na nke abụọ hyperfibrinolysis;

(2) thrombolysis;

D-dimer na-egosipụtakarị ọrụ fibrinolytic.Mmụba ma ọ bụ nke ọma a na-ahụ na hyperfibrinolysis nke abụọ, dị ka ọnọdụ hypercoagulable, gbasaa coagulation intravascular, ọrịa akụrụ, nkwụsị nke akụkụ ahụ, ọgwụgwọ thrombolytic, wdg.

3. Ọ bụrụhaala na enwere thrombosis na-arụ ọrụ na fibrinolytic n'ime arịa ọbara nke ahụ, D-dimer ga-abawanye.

Dị ka ihe atụ: myocardial infarction, ụbụrụ ụbụrụ, pulmonary embolism, venous thrombosis, ịwa ahụ, etuto, gbasaa intravascular coagulation, ọrịa na anụ ahụ necrosis nwere ike iduga ụba D-dimer.Karịsịa maka ndị agadi na ndị ọrịa ụlọ ọgwụ, n'ihi nje bacteria na ọrịa ndị ọzọ, ọ dị mfe ime ka ọbara ọgbụgba na-adịghị mma ma na-eduga n'ịbawanye D-dimer.

4. Ihe dị iche iche nke D-dimer gosipụtara adịghị ezo aka na arụmọrụ na ọrịa a kapịrị ọnụ, kama na njirimara pathological nkịtị nke nnukwu ìgwè ọrịa a na coagulation na fibrinolysis.

N'ụzọ doro anya, nguzobe fibrin jikọtara ọnụ bụ thrombosis.Agbanyeghị, enwere ọtụtụ ọrịa ụlọ ọgwụ nwere ike ime ka sistemu coagulation rụọ ọrụ n'oge ihe omume na mmepe nke ọrịa ahụ.Mgbe a na-emepụta fibrin na-ejikọta ya, a ga-eme ka usoro fibrinolytic rụọ ọrụ na fibrin jikọtara ya ga-eji hydrolyzed iji gbochie nnukwu "mgbakọ" ya.thrombus dị ịrịba ama, nke na-ebute D-dimer dị elu nke ukwuu.Ya mere, D-dimer dị elu abụghị ihe dị mkpa n'ụlọ ọgwụ.Maka ụfọdụ ọrịa ma ọ bụ ndị mmadụ n'otu n'otu, ọ nwere ike ịbụ usoro pathological.