Thrombosis na-enwekarị ọnọdụ atọ ndị a:

1. Obi na arịa ọbara intima mmerụ ahụ

Ọnụnọ nke obi nkịtị na arịa ọbara na-adịchaghị mma ma dịkwa nro, na mkpụrụ ndụ endothelial emebibeghị nwere ike igbochi nrapagide nke platelet na mgbochi ọbara.Mgbe akpụkpọ ahụ dị n'ime mebiri emebi, usoro nhazi nke coagulation nwere ike ịrụ ọrụ n'ọtụtụ ụzọ.

Intima nke mbụ mebiri emebi na-ewepụta ihe na-akpata coagulation anụ ahụ (coagulation factor III), nke na-eme ka sistemu coagulation extrinsic rụọ ọrụ.
Nke abuo, mgbe intima mebiri emebi, mkpụrụ ndụ endothelial na-enweta mmebi, necrosis, na ịwụfu, na-ekpughe eriri collagen n'okpuru endothelium, si otú ahụ na-eme ka coagulation factor XII nke usoro coagulation nke endogenous na-amalite usoro nhazi nke endogenous coagulation.Na mgbakwunye, intima mebiri emebi na-aghọ ihe siri ike, nke na-eme ka ntinye platelet na nrapado.Mgbe platelet ndị ahụ jikọtara ọnụ na-agbawa, a na-ewepụta ihe dị iche iche nke platelet, na usoro nchịkọta coagulation dum na-arụ ọrụ, na-eme ka ọbara na-agbakọta ma na-etolite thrombus.
Ihe dị iche iche anụ ahụ, kemịkalụ na ihe ndị dị ndụ nwere ike imebi intima nke obi, dị ka endocarditis na ezì erysipelas, pulmonary vasculitis in bovine pneumonia, equine parasitic arteritis, injections ugboro ugboro n'otu akụkụ nke vein, mmerụ ahụ na nkwụsị nke mgbidi arịa ọbara. n'oge ịwa ahụ.

2. Mgbanwe na ọkwa ọbara

Nke kachasị na-ezo aka n'ịgba ọsọ ọbara nwayọ, nguzobe vortex na nkwụsị ọbara.
N'okpuru ọnọdụ nkịtị, ọnụọgụ ọbara na-agba ọsọ ngwa ngwa, na mkpụrụ ndụ ọbara uhie, platelet na ihe ndị ọzọ na-etinye uche n'etiti arịa ọbara, nke a na-akpọ axial flow;mgbe ọnụọgụ ọbara na-ebelata, mkpụrụ ndụ ọbara uhie na platelet ga-eru nso na mgbidi arịa ọbara, nke a na-akpọ n'akụkụ, nke na-abawanye thrombosis.ihe ize ndụ na-ebilite.
Ọbara ahụ na-ebelata, mkpụrụ ndụ endothelial na-enwekwa hypoxic siri ike, na-eme ka mmebi na necrosis nke mkpụrụ ndụ endothelial, nkwụsị nke ọrụ ha nke ịmepụta na ịhapụ ihe ndị na-egbochi arịa ọbara, na ikpughe nke collagen, nke na-eme ka usoro coagulation na-arụ ọrụ ma na-akwalite. thrombosis.
Ọbara na-agba nwayọọ nwayọọ nwekwara ike ime ka thrombus a kpụrụ akpụ dị mfe idozi na mgbidi arịa ọbara ma nọgide na-abawanye.

Ya mere, thrombus na-emekarị na veins na-eji nwayọọ nwayọọ na-agba ọsọ na-agba ọsọ ma na-adaba na mmiri ọkụ (na valves venous).Ọbara aortic na-agba ọsọ ngwa ngwa, a naghị ahụkwa thrombus.Dị ka ọnụ ọgụgụ si kwuo, ihe omume nke venous thrombosis bụ ugboro 4 karịa nke thrombosis arterial, na venous thrombosis na-emekarị na nkụchi obi, mgbe a wachara ya ahụ ma ọ bụ na anụmanụ na-arịa ọrịa dina n'ime akwu ogologo oge.
Ya mere, ọ dị oke mkpa iji nyere ụmụ anụmanụ na-arịa ọrịa aka bụ ndị dina ala ruo ogologo oge na mgbe a wachara ya ahụ ime ụfọdụ ihe kwesịrị ekwesị iji gbochie thrombosis.
3. Mgbanwe na njirimara ọbara.

tumadi na-ezo aka na mmụba ọbara coagulation.Dị ka nnukwu ọkụ ọkụ, akpịrị ịkpọ nkụ, wdg na-etinye uche n'ọbara, nnukwu trauma, postpartum, na nnukwu ọbara na-efunahụ mgbe arụchara ọrụ dị ukwuu nwere ike ime ka ọnụ ọgụgụ platelet dị n'ọbara dịkwuo elu, mee ka viscosity ọbara dịkwuo elu, na ịbawanye ọdịnaya nke fibrinogen, thrombin na ihe ndị ọzọ na-akpata coagulation. na mmụba plasma.Ihe ndị a nwere ike ịkwalite thrombosis.