Imeju bụ ebe a na-emepụta ihe dị iche iche nke coagulation, ma nwee ike ịmepụta ma mee ka fibrin lysates na ihe antifibrinolytic na-arụ ọrụ, ma na-arụ ọrụ nchịkwa n'ịkwado nguzozi ike nke usoro coagulation na anticoagulation.Nchọpụta nke index coagulation ọbara na ndị ọrịa nwere ịba ọcha n'anya B gosiri na ọ dịghị ihe dị ịrịba ama na PTAPTT na ndị ọrịa na-adịghị ala ala ịba ọcha n'anya B ma e jiri ya tụnyere ndị nkịtị akara otu (P> 0.05), ma e nwere nnukwu ọdịiche dị na FIB (P <0.05). ).E nwere nnukwu ọdịiche dị na PT, APTT, na FIB n'etiti oke ịba ọcha n'anya B na otu ndị na-achịkwa nkịtị (P<005P<0.01), nke gosipụtara na oke ịba ọcha n'anya B na-ejikọta ya na mbelata nke ọkwa coagulation ọbara.

Nyocha nke ihe kpatara nsonaazụ dị n'elu:

1. Ewezuga ihe IV (Ca *) na cytoplasm, a na-emepụta ihe ndị ọzọ na-eme ka plasma coagulation na imeju;A na-emepụtakwa ihe na-egbochi ọrịa obi (ndị na-egbochi coagulation) dị ka ATIPC, 2-MaI-AT, wdg site na imeju.njikọ cellular.Mgbe mkpụrụ ndụ imeju mebiri ma ọ bụ necrotic na ọkwa dị iche iche, ikike imeju na-emepụta ihe na-eme ka coagulation na-ebelata, na-ebelatakwa ọkwa plasma nke ihe ndị a, na-ebute ihe mgbochi na usoro coagulation.PT bụ ule nyocha nke sistemu coagulation extrinsic, nke nwere ike igosipụta ọkwa, ọrụ na ọrụ nke coagulation factor IV VX na plasma.Mbelata nke ihe ndị dị n'elu ma ọ bụ mgbanwe na ọrụ ha na ọrụ ha aghọwo otu n'ime ihe kpatara PT na-adịte aka na ndị ọrịa nwere ọrịa ịba ọcha n'anya B cirrhosis na ịba ọcha n'anya B. Ya mere, a na-ejikarị PT eme ihe na ụlọ ọgwụ iji gosipụta njikọ nke coagulation. ihe na imeju.

2. N'aka nke ọzọ, na mmebi nke mkpụrụ ndụ imeju na imeju imeju na ndị ọrịa ịba ọcha n'anya B, ọkwa plasmin na plasma na-abawanye n'oge a.Plasmin nwere ike ọ bụghị naanị hydrolyze nnukwu fibrin, fibrinogen na ọtụtụ ihe coagulation dị ka ọzụzụ ihe, XXX, VVII,Ⅱ, wdg, ma na-erikwa nnukwu ihe mgbochi coagulation dị ka ATⅢPC na ndị ọzọ.Ya mere, na mmụba nke ọrịa ahụ, APTT na-agbatị ogologo oge na FIB na-ebelata nke ukwuu na ndị ọrịa ịba ọcha n'anya B.

Na mmechi, nchọpụta nke coagulation indexes dị ka PTAPTTFIB nwere ezigbo mkpa ụlọ ọgwụ maka ikpe ọnọdụ nke ndị ọrịa na-adịghị ala ala ịba ọcha n'anya B, na bụ mmetụta uche na a pụrụ ịdabere na nchọpụta index.