Ahụ nkịtị nwere usoro coagulation zuru oke na mgbochi mgbochi.Sistemụ coagulation na usoro mgbochi ọrịa obi na-ejigide nguzosi ike ike iji hụ na ọbara hemostasis nke anụ ahụ na-agba na nke ọma.Ozugbo coagulation na anticoagulation ọrụ nguzozi na-akpaghasị, ọ ga-eduga na ọbara ọgbụgba na thrombosis ọchịchọ.

1. Ọrụ coagulation nke ahụ

Usoro coagulation bụ nke kachasị ihe mejupụtara ya.A na-akpọ ihe ndị na-etinye aka na coagulation ozugbo.Enwere ihe 13 a mapụtara na coagulation.

Enwere ụzọ mmeghari nke endogenous na ụzọ mgbake exogenous maka ịgbalite ihe coagulation.

A na-ekwenye ugbu a na ịgbalite usoro coagulation exogenous nke sitere na anụ ahụ na-arụ ọrụ dị ukwuu na mmalite nke coagulation.Njikọ chiri anya n'etiti sistemu coagulation nke ime na nke mpụga na-arụ ọrụ dị mkpa n'ịmalite na idobe usoro coagulation.

2. Ọrụ anticoagulant nke ahụ

Usoro mgbochi ọrịa na-agụnye sistemu mgbochi ọrịa cellular na sistemu mgbochi ọbara nke anụ ahụ.

① Sistemụ anticoagulation cell

Na-ezo aka na phagocytosis nke ihe coagulation, ihe anụ ahụ, prothrombin complex na soluble fibrin monomer site na usoro mononuclear-phagocyte.

②Sistemụ anticoagulation nke mmiri ahụ

Gụnyere: serine protease inhibitors, protein C-based protease inhibitors na anụ ahụ na-eme ihe mgbochi ụzọ (TFPI).

3. Fibrinolytic usoro na ọrụ ya

Nke kachasị gụnyere plasminogen, plasmin, plasminogen activator na fibrinolysis inhibitor.

Ọrụ nke usoro fibrinolytic: gbazee mkpịsị fibrin ma hụ na mgbasa ọbara dị mma;sonye na nrụzi anụ ahụ na mmụgharị vaskụla.

4. Ọrụ nke mkpụrụ ndụ endothelial vaskụla na usoro nke coagulation, anticoagulation na fibrinolysis.

① Mepụta ihe dị iche iche na-arụ ọrụ ndụ;

② Na-ahazi coagulation ọbara na ọrụ mgbochi;

③Dezie ọrụ nke fibrinolysis usoro;

④ Mezie esemokwu vaskụla;

⑤ Soro na mediation nke mbufụt;

⑥ Nọgide na-arụ ọrụ nke microcirculation, wdg.

Coagulation na ọrịa anticoagulant

1. Ihe na-adịghị mma na coagulation ihe.

2. Ihe na-adịghị mma nke ihe ndị na-eme ihe na-egbu egbu na plasma.

3. Ihe na-adịghị mma nke ihe fibrinolytic na plasma.

4. Mgbanwe nke mkpụrụ ndụ ọbara.

5. Ọbara ọbara na-adịghị mma.