Enwere ike ịhụ na D-Dimer nwere mkpa nleba anya metụtara mgbagwoju anya na ọganihu nke COVID-19, yabụ kedu ka o si arụ ọrụ na ọrịa ndị ọzọ?

1. venous thromboembolism

A na-eji D-Dimer mee ihe n'ọtụtụ ebe na ọrịa ndị metụtara venous thromboembolism (VTE), dị ka thrombosis miri emi (DVT) na pulmonary embolism (PE).Nnwale D-Dimer na-adịghị mma nwere ike wepụ DVT, na ntinye uche D-Dimer nwekwara ike iji buru amụma nlọghachi nke VTE.Nnyocha ahụ chọpụtara na oke ihe ize ndụ nke nlọghachi azụ VTE na ndị mmadụ nwere itinye uche dị elu bụ okpukpu 4.1 karịa nke ndị mmadụ nwere itinye uche nkịtị.

D-Dimer bụkwa otu n'ime ihe nrịba ama nke PE.Uru amụma ya na-adịghị mma dị oke elu, na ihe ọ pụtara bụ iwepụ nnukwu ọrịa pulmonary embolism, karịsịa na ndị ọrịa nwere obere enyo.Ya mere, maka ndị ọrịa a na-enyo enyo na ọ na-enwe nnukwu ọrịa pulmonary embolism, ultrasonography nke veins miri emi nke obere nsọtụ na nyocha D-Dimer kwesịrị ijikọta.

2. Kesara intravascular coagulation

Mgbakọ intravascular nke na-ekesa (DIC) bụ ọrịa a na-ahụ anya nke ọbara ọgbụgba na ọdịda microcirculatory na-adabere na ọtụtụ ọrịa.Usoro mmepe na-agụnye ọtụtụ usoro dị ka coagulation, anticoagulation, na fibrinolysis.D-Dimer mụbara n'oge mmalite nke nhazi DIC, na ntinye uche ya nọgidere na-abawanye karịa ugboro iri ka ọrịa ahụ na-aga n'ihu.Ya mere, a pụrụ iji D-Dimer mee ihe dị ka otu n'ime ihe ndị bụ isi maka nchọpụta mmalite na nlekota ọnọdụ nke DIC.

3. Aortic dissection

"Nkwekọrịta ndị ọkachamara nke China na nchọpụta na ọgwụgwọ nke dissection aortic" rụtụrụ aka na D-Dimer, dị ka nyocha ụlọ nyocha na-emekarị maka mgbasa ozi aortic (AD), dị ezigbo mkpa maka nchọpụta na nchọpụta dị iche iche nke mgbasa.Mgbe D-Dimer onye ọrịa na-ebili ngwa ngwa, ohere nke ịchọpụta ya ka AD na-abawanye.N'ime awa 24 nke mmalite, mgbe D-Dimer ruru uru dị oke egwu nke 500 μg / L, ikike ya maka ịchọpụta nnukwu AD bụ 100%, nkọwa ya bụ 67%, yabụ enwere ike iji ya dị ka ndenye mwepu maka nyocha nke ọrịa. nnukwu AD.

4. Atherosclerotic Cardiovascular Ọrịa

Atherosclerotic obi ọrịa bụ ọrịa obi nke arteriosclerotic plaque kpatara, gụnyere ST-ngalaba elu nnukwu myocardial infarction, na-abụghị ST-ngalaba elu nnukwu myocardial infarction, na angina akwụsighị ike.Mgbe mgbawa ihe ncheta, ihe necrotic bụ isi dị na plaque na-asọpụta, na-eme ka akụkụ ọbara na-adịghị mma, ịgbalite usoro coagulation, na ụbara D-Dimer.Ndị ọrịa obi na-arịa ọrịa obi nwere D-Dimer dị elu nwere ike ịkọ ihe ize ndụ dị elu nke AMI ma enwere ike iji ya mee ihe ngosi iji hụ ọnọdụ ACS.

5. Usoro ọgwụgwọ thrombolytic

Nnyocha nke Lawter chọpụtara na ọgwụ thrombolytic dị iche iche nwere ike ịbawanye D-Dimer, na mgbanwe ntinye uche ya tupu na mgbe thrombolysis nwere ike iji mee ihe dị ka ihe ngosi maka ikpe ikpe ọgwụgwọ thrombolytic.Ọdịnaya ya na-abawanye ngwa ngwa ruo ọnụ ahịa kachasị elu mgbe thrombolysis gasịrị, wee daa azụ n'oge dị mkpirikpi na mmụba dị ịrịba ama na mgbaàmà ụlọ ọgwụ, na-egosi na ọgwụgwọ ahụ dị irè.

- Ọkwa D-Dimer mụbara nke ukwuu 1 awa ruo 6 awa mgbe thrombolysis maka nnukwu myocardial infarction na cerebral infarction.
N'oge DVT thrombolysis, ọnụ ọgụgụ D-Dimer na-emekarị awa 24 ma ọ bụ mgbe e mesịrị