FIB yog cov lus Askiv luv luv rau fibrinogen, thiab fibrinogen yog qhov ua rau coagulation.Cov ntshav coagulation siab FIB tus nqi txhais tau hais tias cov ntshav nyob rau hauv lub xeev hypercoagulable, thiab thrombus tau yooj yim tsim.
Tom qab tib neeg coagulation mechanism yog qhib, fibrinogen ua fibrin monomer nyob rau hauv qhov kev txiav txim ntawm thrombin, thiab fibrin monomer tuaj yeem sib sau ua ke rau hauv fibrin polymer, uas yog pab rau kev tsim cov ntshav txhaws thiab ua lub luag haujlwm tseem ceeb hauv cov txheej txheem coagulation.
Fibrinogen feem ntau yog tsim los ntawm hepatocytes thiab yog cov protein nrog coagulation muaj nuj nqi.Nws tus nqi ib txwm nyob nruab nrab ntawm 2 ~ 4qL.Fibrinogen yog ib yam khoom uas cuam tshuam nrog kev coagulation, thiab nws qhov kev nce ntxiv feem ntau yog cov tshuaj tiv thaiv tsis tshwj xeeb ntawm lub cev thiab yog qhov muaj feem cuam tshuam rau cov kab mob thromboembolism.
Coagulation FIB tus nqi tuaj yeem nce ntxiv hauv ntau cov kab mob, cov caj ces lossis cov kab mob inflammatory, ntshav lipids, ntshav siab.
Siab, kab mob plawv, ntshav qab zib, tuberculosis, kab mob sib txuas, kab mob plawv, thiab qog nqaij hlav malignant.thaum kev txom nyem los ntawm tag nrho cov kab mob saum toj no yuav ua rau muaj qhov tshwm sim ntawm cov ntshav txhaws.Yog li ntawd, cov ntshav siab coagulation FIB nqi yog hais txog lub xeev ntawm cov ntshav coagulation siab.
Qib fibrinogen siab txhais tau hais tias cov ntshav nyob rau hauv lub xeev ntawm hypercoagulability thiab yog nquag mus rau thrombosis.Fibrinogen tseem hu ua coagulation factor I. Txawm hais tias nws yog endogenous coagulation lossis exogenous coagulation, cov kauj ruam kawg ntawm fibrinogen yuav qhib fibroblasts.Proteins maj mam intertwined rau hauv lub network los tsim cov ntshav txhaws, yog li fibrinogen sawv cev rau kev ua haujlwm ntawm cov ntshav coagulation.
Fibrinogen feem ntau yog tsim los ntawm lub siab thiab tuaj yeem nce siab hauv ntau yam kab mob.Cov caj ces lossis cov kab mob inflammatory muaj xws li ntshav lipids, ntshav siab, kab mob plawv, ntshav qab zib, tuberculosis, kab mob sib txuas, kab mob plawv, thiab qog nqaij hlav malignant yuav nce.Tom qab kev phais loj, vim hais tias lub cev xav tau kev ua haujlwm hemostasis, nws tseem yuav txhawb nqa qhov nce ntawm fibrinogen rau hemostasis.