Qhov laj thawj

1. Kev raug mob plawv endothelial
Kev raug mob ntawm cov hlab ntsha endothelial yog qhov tseem ceeb tshaj plaws thiab feem ntau ua rau kev tsim cov thrombus, thiab nws muaj ntau dua nyob rau hauv rheumatic thiab kis kab mob endocarditis, mob atherosclerotic plaque ulcers, raug mob los yog inflammatory arteriovenous chaw raug mob, thiab lwm yam. Muaj kuj muaj hypoxia, poob siab, sepsis thiab kab mob. endotoxins uas ua rau muaj ntau yam kab mob endogenous thoob plaws lub cev.
Tom qab kev raug mob ntawm daim tawv nqaij, collagen nyob rau hauv lub endothelium activates cov txheej txheem coagulation, ua rau disseminated intravascular coagulation, thiab thrombus cov ntaub ntawv nyob rau hauv lub microcirculation ntawm tag nrho lub cev.

2. Cov ntshav ntws tsis zoo
Nws feem ntau yog hais txog kev ua kom qeeb ntawm cov ntshav khiav thiab tiam ntawm cov eddies hauv cov ntshav khiav, thiab lwm yam, thiab cov activated coagulation yam thiab thrombin ncav cuag cov concentration xav tau rau coagulation hauv cheeb tsam, uas yog conducive rau tsim thrombus.Ntawm lawv, cov hlab ntsha muaj feem cuam tshuam rau thrombus, uas muaj ntau dua rau cov neeg mob plawv tsis ua haujlwm, mob ntev thiab tom qab pw tsaug zog.Tsis tas li ntawd, cov ntshav khiav hauv lub plawv thiab cov hlab ntsha yog nrawm, thiab nws tsis yooj yim rau kev tsim cov thrombus.Txawm li cas los xij, thaum cov ntshav ntws nyob rau hauv sab laug atrium, aneurysm, los yog ceg ntawm cov hlab ntsha qeeb thiab eddy tam sim no tshwm sim thaum lub sij hawm mitral valve stenosis, nws kuj yog thrombosis.

3. nce ntshav coagulation
Feem ntau, cov platelets thiab coagulation yam nyob rau hauv cov ntshav nce, los yog cov kev ua ntawm lub fibrinolytic system txo, ua rau ib tug hypercoagulable xeev nyob rau hauv cov ntshav, uas yog ntau ntau nyob rau hauv hereditary thiab tau txais hypercoagulable xeev.

4. Hereditary hypercoagulable xeev
Nws muaj feem cuam tshuam txog kev hloov pauv ntawm cov noob caj noob ces, qhov tsis xws ntawm cov protein C thiab cov protein S, thiab lwm yam. Ntawm lawv, feem ntau ntawm V gene mutation, qhov kev hloov pauv ntawm cov noob no tuaj yeem ncav cuag 60% hauv cov neeg mob uas muaj cov kab mob sib sib zog nqus thrombosis.

5. Tau txais lub xeev hypercoagulable
Feem ntau pom nyob rau hauv pancreatic cancer, mob ntsws cancer, mob cancer mis, prostate cancer, gastric cancer thiab lwm yam kab mob metastatic advanced malignant hlav, tshwm sim los ntawm kev tso tawm ntawm procoagulant yam los ntawm cov qog nqaij hlav cancer;Nws kuj tuaj yeem tshwm sim hauv kev raug mob hnyav, kub hnyiab, kev phais loj lossis tom qab yug me nyuam Thaum muaj ntshav ntau, thiab hauv cov xwm txheej xws li gestational hypertension, hyperlipidemia, coronary atherosclerosis, haus luam yeeb, thiab rog.