1. Prothrombin Sijhawm (PT)

Nws feem ntau qhia txog cov xwm txheej ntawm exogenous coagulation system, uas INR feem ntau siv los saib xyuas qhov ncauj anticoagulants.PT yog qhov taw qhia tseem ceeb rau kev kuaj mob ntawm lub xeev prethrombotic, DIC thiab kab mob siab.Nws yog siv los ua kev tshuaj ntsuam xyuas rau exogenous coagulation system thiab kuj yog ib qho tseem ceeb ntawm kev kho qhov ncauj anticoagulation therapy koob tshuaj.

PTA <40% qhia tias loj necrosis ntawm daim siab hlwb thiab txo synthesis ntawm coagulation yam.Piv txwv li, 30%

Lub prolongation yog pom nyob rau hauv:

a.Kev puas tsuaj rau daim siab dav thiab loj heev yog vim qhov tsim ntawm prothrombin thiab muaj feem cuam tshuam rau cov ntshav txhaws.

b.Tsis txaus VitK, VitK yuav tsum tau ua kom cov khoom sib txuas II, VII, IX, thiab X. Thaum VitK tsis txaus, cov khoom siv txo qis thiab lub sijhawm prothrombin ntev.Nws kuj pom nyob rau hauv obstructive jaundice.

C. DIC (diffuse intravascular coagulation), uas siv cov coagulation ntau ntau vim yog qhov dav ntawm microvascular thrombosis.

d.Neonatal spontaneous hemorrhage, congenital prothrombin tsis muaj anticoagulant kho.

Shorten pom hauv:

Thaum cov ntshav nyob rau hauv lub xeev hypercoagulable (xws li thaum ntxov DIC, myocardial infarction), thrombotic kab mob (xws li cerebral thrombosis), thiab lwm yam.

 

2. Thrombin lub sij hawm (TT)

Feem ntau qhia txog lub sijhawm thaum fibrinogen hloov mus ua fibrin.

Kev ncua ntev yog pom nyob rau hauv: nce heparin lossis heparinoid tshuaj, nce AT-III kev ua, qhov txawv txav thiab zoo ntawm fibrinogen.DIC hyperfibrinolysis theem, qis (tsis muaj) fibrinogenemia, txawv txav hemoglobinemia, ntshav fibrin (proto) degradation khoom (FDPs) nce.

Qhov txo qis tsis muaj qhov tseem ceeb hauv kev kho mob.

 

3. Ua kom lub sijhawm ib nrab thromboplastin (APTT)

Nws feem ntau qhia txog qhov xwm txheej ntawm endogenous coagulation system thiab feem ntau siv los saib xyuas cov tshuaj heparin.Kev xav txog qib ntawm coagulation yam VIII, IX, XI, XII hauv plasma, nws yog ib qho kev ntsuam xyuas rau endogenous coagulation system.APTT feem ntau yog siv los saib xyuas heparin anticoagulation therapy.

Lub prolongation yog pom nyob rau hauv:

a.Tsis muaj coagulation yam VIII, IX, XI, XII:

b.Coagulation factor II, V, X thiab fibrinogen txo ob peb;

C. Muaj cov tshuaj anticoagulant xws li heparin;

d, fibrinogen degradation khoom nce;ib, DIC.

Shorten pom hauv:

Hypercoagulable xeev: Yog hais tias cov tshuaj procoagulant nkag mus rau hauv cov ntshav thiab cov kev ua ntawm coagulation yam nce, thiab lwm yam.:

 

4.Plasma fibrinogen (FIB)

Feem ntau qhia txog cov ntsiab lus ntawm fibrinogen.Plasma fibrinogen yog cov coagulation protein nrog cov ntsiab lus siab tshaj plaws ntawm tag nrho cov coagulation yam, thiab nws yog ib tug mob theem teb yam tseem ceeb.

Nce pom nyob rau hauv: kub hnyiab, ntshav qab zib, mob mob, mob tuberculosis, mob cancer, subacute kab mob endocarditis, cev xeeb tub, mob ntsws, cholecystitis, pericarditis, sepsis, nephrotic syndrome, uremia, mob myocardial infarction.

Kev txo qis pom nyob rau hauv: Congenital fibrinogen abnormality, DIC nkim theem hypocoagulation, thawj fibrinolysis, mob siab mob siab, siab cirrhosis.

 

5.D-Dimer (D-Dimer)

Nws tsuas yog qhia txog kev ua haujlwm ntawm fibrinolysis thiab yog ib qho qhia los txiav txim seb muaj lossis tsis muaj thrombosis thiab theem nrab fibrinolysis hauv lub cev.

D-dimer yog ib yam khoom degradation ntawm cross-linked fibrin, uas nce hauv plasma tsuas yog tom qab thrombosis, yog li nws yog ib qho tseem ceeb molecular cim rau kev kuaj mob thrombosis.

D-dimer tau nce ntau hauv cov fibrinolysis theem nrab hyperactivity, tab sis tsis nce hauv thawj fibrinolysis hyperactivity, uas yog ib qho tseem ceeb qhia rau qhov txawv ntawm ob.

Qhov nce yog pom nyob rau hauv cov kab mob xws li cov hlab ntsha sib sib zog nqus thrombosis, pulmonary embolism, thiab DIC theem nrab hyperfibrinolysis.