Xyoo 2019 tus kab mob tshiab coronavirus mob ntsws (COVID-19) tau kis thoob ntiaj teb.Cov kev tshawb fawb yav dhau los tau pom tias tus kab mob coronavirus tuaj yeem ua rau muaj kev cuam tshuam ntawm coagulation, feem ntau tshwm sim raws li lub sij hawm ntev activated ib nrab thromboplastin lub sij hawm (APTT), thrombocytopenia, D-dimer (DD) nce qib thiab tshaj tawm intravascular coagulation (DIC), uas cuam tshuam nrog kev tuag ntau dua.

Kev soj ntsuam meta-tshaj tawm tsis ntev los no ntawm kev ua haujlwm ntawm coagulation hauv cov neeg mob nrog COVID-19 (suav nrog 9 qhov kev tshawb fawb rov qab nrog tag nrho ntawm 1 105 tus neeg mob) tau pom tias piv nrog cov neeg mob me, cov neeg mob hnyav COVID-19 muaj qhov tseem ceeb DD ntau dua, Prothrombin time (PT) tau ntev;nce DD yog ib qho kev pheej hmoo rau exacerbation thiab muaj feem cuam tshuam rau kev tuag.Txawm li cas los xij, cov lus hais saum toj no Meta-analysis suav nrog kev tshawb fawb tsawg dua thiab suav nrog tsawg dua cov kev tshawb fawb.Tsis ntev los no, ntau qhov kev tshawb fawb soj ntsuam loj ntawm kev ua haujlwm coagulation hauv cov neeg mob nrog COVID-19 tau tshaj tawm, thiab cov yam ntxwv coagulation ntawm cov neeg mob nrog COVID-19 tau tshaj tawm hauv ntau qhov kev tshawb fawb kuj tsis yog raws nraim.

Ib txoj kev tshawb fawb tsis ntev los no raws li cov ntaub ntawv hauv tebchaws tau pom tias 40% ntawm cov neeg mob COVID-19 muaj kev pheej hmoo siab rau venous thromboembolism (VTE), thiab 11% ntawm cov neeg mob muaj kev pheej hmoo siab txhim kho yam tsis muaj kev tiv thaiv.VTE.Cov txiaj ntsig ntawm lwm txoj kev tshawb fawb kuj tau qhia tias 25% ntawm cov neeg mob hnyav COVID-19 tau tsim VTE, thiab cov neeg tuag ntawm cov neeg mob VTE tau siab txog 40%.Nws qhia tau hais tias cov neeg mob COVID-19, tshwj xeeb tshaj yog cov neeg mob hnyav lossis mob hnyav, muaj kev pheej hmoo siab ntawm VTE.Qhov laj thawj yog vim li cas cov neeg mob hnyav thiab mob hnyav muaj ntau yam kab mob hauv qab, xws li keeb kwm ntawm cerebral infarction thiab malignant qog, uas yog tag nrho cov kev pheej hmoo rau VTE, thiab cov neeg mob hnyav thiab mob hnyav tau pw hauv txaj ntev ntev, sedated, immobilized. , thiab muab tso rau hauv ntau yam khoom siv.Kev kho mob xws li cov hlab ntsha kuj tseem muaj feem cuam tshuam rau thrombosis.Yog li ntawd, rau cov neeg mob hnyav thiab mob hnyav rau COVID-19, kev tiv thaiv txhua yam ntawm VTE, xws li elastic stockings, intermittent inflatable twj, thiab lwm yam, tuaj yeem ua tau;Nyob rau tib lub sijhawm, tus neeg mob cov keeb kwm kho mob yav dhau los yuav tsum tau nkag siab tag nrho, thiab tus neeg mob lub coagulation kev ua haujlwm yuav tsum tau soj ntsuam raws sijhawm.ntawm cov neeg mob, prophylactic anticoagulation tuaj yeem pib yog tias tsis muaj contraindications

Cov txiaj ntsig tam sim no qhia tias cov kab mob coagulation muaj ntau dua hauv cov neeg mob hnyav, mob hnyav, thiab tuag rau COVID-19.Platelet suav, DD thiab PT qhov tseem ceeb muaj feem cuam tshuam nrog cov kab mob hnyav thiab tuaj yeem siv los ua cov cim ceeb toom ntxov ntawm tus kab mob deterioration thaum mus pw hauv tsev kho mob.