Ntshav Anticoagulants yog dab tsi?

Tshuaj reagents lossis tshuaj uas tuaj yeem tiv thaiv cov ntshav coagulation yog hu ua anticoagulants, xws li ntuj anticoagulants (heparin, hirudin, thiab lwm yam), Ca2 + chelating agents (sodium citrate, potassium fluoride).Cov tshuaj anticoagulants uas nquag siv muaj xws li heparin, ethylenediaminetetraacetate (EDTA ntsev), citrate, oxalate, thiab lwm yam. Hauv kev siv tswv yim, cov tshuaj tiv thaiv coagulants yuav tsum raug xaiv raws li kev xav tau sib txawv kom tau txais cov txiaj ntsig zoo.

Kev txhaj tshuaj Heparin

Kev txhaj tshuaj heparin yog ib qho tshuaj tiv thaiv coagulant.Nws yog siv los txo qhov muaj peev xwm ntawm cov ntshav txhaws thiab pab tiv thaiv cov hlab ntsha puas tsuaj los ntawm kev tsim cov hlab ntsha.Cov tshuaj no qee zaum hu ua ntshav thinner, txawm hais tias nws tsis tau dilute cov ntshav.Heparin tsis yaj cov ntshav txhaws uas twb tsim lawm, tab sis nws tuaj yeem tiv thaiv kom tsis txhob loj dua, uas tuaj yeem ua rau muaj teeb meem loj dua.

Heparin yog siv los tiv thaiv lossis kho qee yam kab mob vascular, plawv thiab ntsws.Heparin kuj tseem siv los tiv thaiv cov ntshav coagulation thaum lub sij hawm qhib lub plawv phais, lub plawv bypass phais, raum dialysis thiab ntshav.Nws yog siv rau hauv cov koob tshuaj tsawg los tiv thaiv thrombosis hauv qee cov neeg mob, tshwj xeeb tshaj yog cov neeg uas yuav tsum tau txais qee hom kev phais lossis yuav tsum tau pw hauv txaj ntev.Heparin kuj tuaj yeem siv los kuaj xyuas thiab kho cov kab mob ntshav loj hu ua disseminated intravascular coagulation.

Nws tsuas tuaj yeem yuav los ntawm kws kho mob cov tshuaj.

EDTC ntsev

Ib yam tshuaj uas khi qee yam hlau ions, xws li calcium, magnesium, lead, thiab hlau.Nws yog siv tshuaj los tiv thaiv kev kuaj ntshav los ntawm kev txhaws thiab tshem tawm calcium thiab txhuas los ntawm lub cev.Nws kuj yog siv los tiv thaiv cov kab mob los ntawm kev tsim biofilms (cov txheej nyias nyias txuas rau saum npoo).Nws yog ib tug chelate agent.Kuj hu ua ethylene diacetic acid thiab ethylene diethylenediamine tetraacetic acid.

EDTA-K2 pom zoo los ntawm International Hematology Standardization Committee muaj cov solubility siab tshaj plaws thiab ceev tshaj anticoagulation ceev.