Tom qab thrombosis tau tsim, nws cov qauv hloov pauv raws li kev ua ntawm fibrinolytic system thiab ntshav ntws poob siab thiab rov tsim dua tshiab ntawm lub cev.
Muaj 3 hom kev hloov pauv zaum kawg hauv lub thrombus:
1. soften, yaj, nqus
Tom qab lub thrombus tsim, cov fibrin nyob rau hauv nws absorbs ib tug loj npaum li cas ntawm plasmin, thiaj li hais tias cov fibrin nyob rau hauv lub thrombus ua ib tug soluble polypeptide thiab dissolves, thiab lub thrombus softens.Nyob rau tib lub sij hawm, vim hais tias cov neutrophils nyob rau hauv lub thrombus disintegrate thiab tso tawm proteolytic enzymes, lub thrombus kuj yuav yaj thiab softened.
Cov thrombus me me dissolves thiab liquefies, thiab tuaj yeem nqus tau los yog ntxuav tawm los ntawm cov hlab ntsha yam tsis muaj kab.
Qhov loj ntawm cov thrombus yog softened thiab yooj yim ntog los ntawm cov ntshav khiav los ua ib tug embolus.Lub emboli thaiv cov hlab ntsha sib xws nrog cov ntshav khiav, uas tuaj yeem ua rau embolism, thaum cov seem seem tau teeb tsa.
2. Mechanization thiab Recanalization
Loj thrombi tsis yooj yim rau yaj thiab nqus tag nrho.Feem ntau, nyob rau hauv 2 mus rau 3 hnub tom qab tsim thrombus, granulation cov ntaub so ntswg loj hlob los ntawm lub puas vascular intima uas lub thrombus txuas, thiab maj mam hloov lub thrombus, uas yog hu ua lub koom haum thrombus.
Thaum lub thrombus tsim, lub thrombus shrinks los yog ib feem dissolves, thiab ib tug fissure yog feem ntau tsim nyob rau hauv lub thrombus los yog nruab nrab ntawm lub thrombus thiab lub hlab ntsha phab ntsa, thiab saum npoo yog them los ntawm proliferating vascular endothelial hlwb, thiab thaum kawg ib los yog ob peb cov hlab ntsha me. uas sib txuas lus nrog thawj cov hlab ntsha yog tsim.Recanalization ntawm cov ntshav ntws yog hu ua recanalization ntawm thrombus.
3. Calcification
Ib qho me me ntawm cov thrombi uas tsis tuaj yeem ua kom yaj tag lossis tsim tau tuaj yeem ua rau nag thiab calcified los ntawm calcium ntsev, tsim cov pob zeb tawv uas muaj nyob hauv cov hlab ntsha, hu ua phleboliths lossis arterioliths.
Cov nyhuv ntawm cov ntshav txhaws ntawm lub cev
Thrombosis muaj ob yam cuam tshuam rau lub cev.
1. Nyob rau sab ntxiv
Thrombosis yog tsim ntawm cov hlab ntsha tawg, uas muaj cov nyhuv hemostatic;thrombosis ntawm cov hlab ntsha me nyob ib ncig ntawm lub inflammatory foci tuaj yeem tiv thaiv kev sib kis ntawm cov kab mob pathogenic thiab co toxins.
2. Kev poob qis
Kev tsim cov thrombus nyob rau hauv cov hlab ntsha tuaj yeem thaiv cov hlab ntsha, ua rau cov nqaij mos thiab lub cev ischemia thiab infarction;
Thrombosis tshwm sim ntawm lub plawv valve.Vim lub koom haum ntawm thrombus, lub valve ua hypertrophic, shrunken, adhered, thiab hardened, ua rau valvular mob plawv thiab cuam tshuam lub plawv ua haujlwm;
Lub thrombus yog ib qho yooj yim kom poob tawm thiab tsim ib qho embolus, uas khiav nrog cov ntshav khiav thiab tsim ib qho embolism nyob rau hauv qee qhov chaw, uas ua rau nws kim heev infarction;
Loj microthrombosis nyob rau hauv microcirculation tuaj yeem ua rau mob hnyav heev thiab poob siab.