1. Plasma D-dimer assay yog ib qho kev ntsuam xyuas kom nkag siab txog kev ua haujlwm fibrinolytic theem nrab.
Kev soj ntsuam txoj cai: Anti-DD monoclonal antibody yog coated ntawm latex hais.Yog hais tias muaj D-dimer nyob rau hauv receptor plasma, antigen-antibody cov tshuaj tiv thaiv yuav tshwm sim, thiab latex particles yuav aggregate.Txawm li cas los xij, qhov kev sim no tuaj yeem ua rau muaj txiaj ntsig zoo rau kev los ntshav nrog kev tsim cov ntshav txhaws, yog li nws muaj qhov tshwj xeeb qis thiab siab rhiab heev.
2. Muaj ob qhov chaw ntawm D-dimer hauv vivo
(1) Hypercoagulable xeev thiab theem nrab hyperfibrinolysis;
(2) thrombolysis;
D-dimer feem ntau qhia txog kev ua haujlwm fibrinolytic.Nce los yog zoo pom nyob rau hauv theem nrab hyperfibrinolysis, xws li hypercoagulable xeev, disseminated intravascular coagulation, kab mob raum, kev hloov hauv lub cev, kev kho thrombolytic, thiab lwm yam.
3. Tsuav yog muaj thrombosis nquag thiab ua haujlwm fibrinolytic hauv lub cev cov hlab ntsha, D-dimer yuav nce.
Piv txwv li: myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, phais, qog, disseminated intravascular coagulation, kab mob thiab cov ntaub so ntswg necrosis tuaj yeem ua rau muaj D-dimer.Tshwj xeeb tshaj yog rau cov neeg laus thiab cov neeg mob pw hauv tsev kho mob, vim yog cov kab mob bacteremia thiab lwm yam kab mob, nws yooj yim ua rau cov ntshav coagulation tsis zoo thiab ua rau muaj D-dimer.
4. Qhov tshwj xeeb xav tau los ntawm D-dimer tsis yog hais txog kev ua haujlwm hauv cov kab mob tshwj xeeb, tab sis rau cov yam ntxwv ntawm cov kab mob loj ntawm pawg kab mob no nrog coagulation thiab fibrinolysis.
Raws li txoj cai, kev tsim ntawm cross-linked fibrin yog thrombosis.Txawm li cas los xij, muaj ntau yam kab mob uas tuaj yeem ua rau lub coagulation system thaum lub sij hawm tshwm sim thiab kev loj hlob ntawm tus kab mob.Thaum tus ntoo khaub lig-txuas fibrin raug tsim, cov txheej txheem fibrinolytic yuav qhib thiab cov ntoo khaub lig-txuas fibrin yuav raug hydrolyzed los tiv thaiv nws loj "sau".(kev kho mob tseem ceeb thrombus), ua rau muaj qhov nce siab D-dimer.Yog li, qhov siab D-dimer tsis tas yuav yog qhov tseem ceeb hauv kev kho mob thrombosis.Rau qee cov kab mob lossis cov tib neeg, nws yuav yog cov txheej txheem pathological.